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RHHBY

Roche

$0.00

(0.00%)

13:02
10/21/18
10/21
13:02
10/21/18
13:02

Genentech's Tecentriq, Abraxane combo demonstrates positive Phase III results

Genentech, a member of the Roche, announced positive results from the Phase III IMpassion130 study of Tecentriq plus chemotherapy - Abraxane - for the initial treatment of unresectable locally advanced or metastatic triple-negative breast cancer. The Tecentriq and chemotherapy combination significantly reduced the risk of disease worsening or death compared with chemotherapy alone in all randomized patients and the PD-L1-positive population, a subgroup determined by PD-L1 biomarker testing. At this interim analysis, statistical significance was not met for overall survival in the ITT population, but showed a clinically meaningful 9.5-month OS improvement in the PD-L1-positive population. Due to the hierarchical statistical design, results in the PD-L1-positive population were not formally tested. Follow-up will continue until the next planned analysis. Safety in the Tecentriq plus nab-paclitaxel arm appeared consistent with the known safety profiles of the individual medicines, and no new safety signals were identified with the combination.

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    Dec

RHHBY Roche
$0.00

(0.00%)

10/03/18
BARD
10/03/18
NO CHANGE
Target $348
BARD
Neutral
Risdiplam data incrementally negative for Biogen, says Baird
Biogen analyst Brian Skorney views this morning's risdiplam data for use in treating spinal muscular atrophy patients as incrementally negative for Biogen (BIIB). The data from PTC Therapeutics (PTCT) and PTC Therapeutics (RHHBY) are compelling so far, and suggest that risdiplam could impact the market share of Biogen's Spinraza, if it comes to market, Skorney tells investors in a research note. He highlights risdiplam's convenience as an oral small molecule and says the Phase II data "continues to impress." The analyst keeps a Neutral rating on Biogen with a $348 price target. The stock in afternoon trading is up $6.90, or 2%, to $352.31.
10/08/18
SBSH
10/08/18
NO CHANGE
Target $470
SBSH
Buy
Biogen price target lowered to $470 from $483 at Citi
Citi analyst Robyn Karnauskas lowered her price target for Biogen (BIIB) to $470 after reducing her assumptions for Rituxan/Gazyva co-promotion profits to reflect greater erosion from biosimilar versions of Rituxan that are expected to launch late 2018/early 2019. The analyst points out that consensus estimates are not modeling significant co-promotion profit erosion from Rituxan biosimilars. However, the Roche (RHHBY) consensus for Rituxan has steep declines in Rituxan sales, Karnauskas tells investors in a research note. The analyst now models a 45% total decline in Rituxan/Gazyva U.S. sales over 2018-2023. She keeps a Buy rating on Biogen.
10/15/18
RBCM
10/15/18
NO CHANGE
RBCM
Sector Perform
Roche breast cancer data could pressure Puma shares, says RBC Capital
RBC Capital analyst Kennen MacKay thinks the data presented this morning by Roche's (RHHBY) Genentech could pressure shares of Puma Biotechnology (PBYI) today. Genentech announced the Phase III Katherine study met its primary endpoint, showing Kadcyla as a single agent reduced the risk of disease recurrence or death compared to Herceptin as an adjuvant treatment in people with HER2-positive early breast cancer who have residual disease present following neoadjuvant treatment. Kadcyla's ultimate entry into the HER2-positive adjuvant setting could complicate the positioning of Puma's Nerlynx, MacKay tells investors in a research note. He keeps a Sector Perform rating on shares of Puma, which are down 4%, or $1.55, to $41.14 in morning trading.
10/16/18
WELS
10/16/18
NO CHANGE
WELS
Drug price in ads not impactful, may cause confusion, says Wells Fargo
Wells Fargo analyst David Maris acknowledges that the U.S. Department of Health and Human Services' proposal to include drug prices in advertisements has a "noble goal" of making drugs more affordable and keeping patients well informed. However, given how different list prices are relative to out of pocket costs, "one must ask if this is increasing transparency or likely going to lead to more confusion," he contends. The analyst also believes that the unintended consequence could be worse care, while noting that the drug price information will likely fall into the category of the side effect information in drug ads currently, tuned out by many and will have no material impact. While he supports the idea of increased transparency, Maris wonders whether the potential benefit is not outweighed by the potential negative for the most vulnerable. Publicly traded companies in the space include AstraZeneca (AZN), Bristol-Myers (BMY), Eli Lilly (LLY), GlaxoSmithKline (GSK), Johnson & Johnson (JNJ), Merck (MRK), Novartis (NVS), Pfizer (PFE), Roche (RHHBY) and Sanofi (SNY).

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GLD

SPDR Gold Trust

$113.66

-0.82 (-0.72%)

17:51
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SPDR Gold Trust holdings rise to 762.00MT from 755.23MT »

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TSLA

Tesla

$331.15

-19.54 (-5.57%)

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Periodicals
Tesla legal executive with regulatory experience leaving, Bloomberg says »

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HUYA

Huya

$18.50

-0.5 (-2.63%)

17:34
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Huya reports Q3 average mobile MAUs 49.4M, up 28.2% from last year »

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VLKAY

Volkswagen

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Daimler AG

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Periodicals
Trump close to auto tariffs in a move that may have 'massive' fallout, BI says »

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Volkswagen

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DDAIF

Daimler AG

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NSANY

Nissan

$0.00

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TM

Toyota

$115.48

-1.83 (-1.56%)

F

Ford

$9.49

0.11 (1.17%)

HMC

Honda

$28.16

-0.34 (-1.19%)

GM

General Motors

$35.71

0.01 (0.03%)

FCAU

Fiat Chrysler

$15.78

-0.48 (-2.95%)

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MPVD

Mountain Province Diamonds

$1.42

-0.03 (-2.07%)

17:32
11/12/18
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17:32
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17:32
Earnings
Mountain Province Diamonds reports Q3 EPS 8c, one estimate 6c »

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HUYA

Huya

$18.50

-0.5 (-2.63%)

17:32
11/12/18
11/12
17:32
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17:32
Earnings
Breaking Earnings news story on Huya »

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  • 12

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YY

YY

$61.39

-3.34 (-5.16%)

17:32
11/12/18
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17:32
Earnings
Breaking Earnings news story on YY »

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HUYA

Huya

$18.50

-0.5 (-2.63%)

17:31
11/12/18
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17:31
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17:31
Earnings
Huya reports Q3 EPS 4c, consensus 4c »

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YY

YY

$61.39

-3.34 (-5.16%)

17:31
11/12/18
11/12
17:31
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17:31
Earnings
YY reports Q3 adjusted income per ADS $1.76, consensus $1.67 »

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CVX

Chevron

$117.47

-2.065 (-1.73%)

, XOM

Exxon Mobil

$79.87

-1.01 (-1.25%)

17:28
11/12/18
11/12
17:28
11/12/18
17:28
Periodicals
Breaking Periodicals news story on Chevron, Exxon Mobil »

Exxon Mobil and Chevron…

CVX

Chevron

$117.47

-2.065 (-1.73%)

XOM

Exxon Mobil

$79.87

-1.01 (-1.25%)

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ESS

Essex Property Trust

$254.54

0.59 (0.23%)

17:26
11/12/18
11/12
17:26
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17:26
Hot Stocks
Essex Property Trust sees no significant damage to CA portfolio from fires »

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ROAN

Roan Resources

$15.90

(0.00%)

17:25
11/12/18
11/12
17:25
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17:25
Hot Stocks
Roan Resources sees Q4 production 52-56 MBoe/d »

The Company is projecting…

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ROAN

Roan Resources

$15.90

(0.00%)

17:24
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Hot Stocks
Roan Resources reports Q3 total production up 30% to 46.5 MBoe/d »

Liquids production…

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ROAN

Roan Resources

$15.90

(0.00%)

17:23
11/12/18
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17:23
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Earnings
Roan Resources reports Q3 adjusted EPS 21c, consensus 24c »

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INTC

Intel

$46.66

-1.44 (-2.99%)

17:19
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Hot Stocks
Intel accelerates launch of multimode modem to support 5G rollouts »

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KRNT

Kornit Digital

$19.15

-0.88 (-4.39%)

17:18
11/12/18
11/12
17:18
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17:18
Earnings
Kornit Digital sees Q4 revenue $37M-$39M, consensus $38.09M »

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  • 12

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UGI

UGI Corporation

$56.47

0.45 (0.80%)

17:18
11/12/18
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17:18
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17:18
Earnings
Breaking Earnings news story on UGI Corporation »

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  • 13

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APU

AmeriGas

$36.63

-0.285 (-0.77%)

17:17
11/12/18
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17:17
Hot Stocks
Breaking Hot Stocks news story on AmeriGas »

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UGI

UGI Corporation

$56.47

0.45 (0.80%)

17:17
11/12/18
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17:17
Earnings
UGI Corporation reports Q4 EPS 14c, consensus (4c) »

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APU

AmeriGas

$36.63

-0.285 (-0.77%)

17:17
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Earnings
AmeriGas reports Q4 EPS (46c) vs (32c) last year »

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  • 13

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SOR

Source Capital

$37.94

0.26 (0.69%)

17:02
11/12/18
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17:02
Hot Stocks
Source Capital declares $3.20 per share special dividend »

Source Capital declared a…

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YRD

Yirendai

$15.47

-1.75 (-10.16%)

17:01
11/12/18
11/12
17:01
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17:01
Earnings
Yirendai reports Q3 adjusted income per ADS 87c, consensus 52c »

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  • 12

    Nov

LTM

Latam Airlines

$8.96

-0.39 (-4.17%)

17:00
11/12/18
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17:00
Hot Stocks
Latam Airlines reports October passenger traffic up 1.5% »

LATAM Airlines Group …

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  • 21

    Nov

ETON

Eton Pharmaceuticals

$0.00

(0.00%)

16:53
11/12/18
11/12
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16:53
Syndicate
Eton Pharmaceuticals 3.6M share IPO priced at $6.00 »

National Securities acted…

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ENR

Energizer

$60.18

-1.235 (-2.01%)

16:49
11/12/18
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Hot Stocks
Energizer names Patrick Moore chairman of the board »

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