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VTGN

VistaGen Therapeutics

$1.93

-0.235 (-10.85%)

09:10
10/25/18
10/25
09:10
10/25/18
09:10

VistaGen Therapeutics acquires license, worldwide rights to PH10 from Pherin

VistaGen Therapeutics announced that the company has exercised its option to acquire from Pherin Pharmaceuticals the exclusive license for worldwide rights to develop and commercialize PH10, a first-in-class, intranasally administered neuroactive steroid, with rapid-onset antidepressant effects for treatment of major depressive disorder, or MDD, demonstrated in a phase 2a study. The company secured the option for PH10 concurrently with its previously announced license agreement with Pherin for worldwide rights to develop and commercialize PH94B, also a first-in-class neuroactive pherine, which VistaGen is preparing for pivotal Phase 3 development as a nasal spray for acute on-demand treatment of social anxiety disorder, or SAD. PH10 activates nasal chemosensory receptors that in turn engage GABA and CRH neurons in the limbic amygdala system. The activation of these neural circuits is believed to have the potential to lead to a rapid antidepressant effect. In connection with the consummation of the license and option agreements, VistaGen issued to Pherin $2M of its unregistered common stock.

VTGN VistaGen Therapeutics
$1.93

-0.235 (-10.85%)

05/24/18
OPCO
05/24/18
INITIATION
Target $6
OPCO
Outperform
VistaGen Therapeutics initiated with an Outperform at Oppenheimer
Oppenheimer analyst Jay Olson started VistaGen Therapeutics with an Outperform rating and $6 price target. The company is "underappreciated and undervalued, with a novel, potentially best-in-class, rapid acting oral antidepressant," Olson tells investors in a research note. He believes AV-101 may offer ketamine-like efficacy without the side effects or inconvenience and that trial readouts by mid-2019 could unlock "substantial shareholder value."
05/25/18
05/25/18
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Enanta (ENTA) initiated with an Outperform at Oppenheimer. 2. VistaGen Therapeutics (VTGN) initiated with an Outperform at Oppenheimer. 3. Engility (EGL) initiated with a Buy at Stifel. 4. ManTech (MANT) initiated with a Hold at Stifel. 5. SAIC (SAIC) initiated with a Hold at Stifel. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, Reference Link
06/27/18
MAXM
06/27/18
INITIATION
Target $6
MAXM
Buy
VistaGen Therapeutics initiated with a Buy at Maxim
Maxim initiated VistaGen Therapeutics with a Buy and $6 price target.
06/27/18
MAXM
06/27/18
INITIATION
Target $6
MAXM
Buy
VistaGen Therapeutics initiated with a Buy at Maxim
As reported earlier, Maxim analyst Caroline Palomeque initiated VistaGen Therapeutics (VTGN) with a Buy rating and a price target of $6 based on its lead drug candidate, AV-101, an oral antidepressant targeting modulation of the NMDA receptor which is an emerging new class of antidepressants. The analyst notes that while Johnson & Johnson (JNJ) and Allergan (AGN) have first mover advantage in the NMDA class, their respective intranasal and IV in-office administration differentiates AV-101 as an oral at-home alternative. Palomeque notes the company's is progressing with its clinical development, as AV-101 undergoes phase 2 studies in treatment resistant major depressive disorder and adjunctive therapy in frontline failed patients, with data expected in the second half of this year and first half of 2019 respectively.

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