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BPMC

Blueprint Medicines

$56.38

-3.89 (-6.45%)

07:25
11/15/18
11/15
07:25
11/15/18
07:25

Blueprint Medicines to hold a conference call

Management presents updated results from the NAVIGATOR Trial of Avapritinib in advanced BIST presented at the Connective Tissue Oncology Society (CTOS) Annual Meeting on a conference call to be held on November 15 at 7:30 am. Webcast Link

  • 15

    Nov

BPMC Blueprint Medicines
$56.38

-3.89 (-6.45%)

09/24/18
LEER
09/24/18
INITIATION
Target $105
LEER
Outperform
Blueprint Medicines initiated with an Outperform at Leerink
Leerink analyst Andrew Berens started Blueprint Medicines with an Outperform rating and $105 price target.
09/26/18
PIPR
09/26/18
NO CHANGE
Target $200
PIPR
Overweight
Loxo RET inhibitor still looks superior to Blueprint's, says Piper Jaffray
Loxo Oncology (LOXO) provided an update of the Phase I/II Libretto study of LOXO-292, the company's RET inhibitor and the vast majority of the current valuation, Piper Jaffray analyst Tyler Van Buren tells investors in a research note. While the overall response rate dropped slightly from 77% to 68% in more patients, it still appears superior to Blueprint Medicines' (BPMC) competing BLU-667, which has thus far demonstrated a 47% response rate in a similar patient population, the analyst contends. Van Buren adds that he's unconcerned by the two new grade three adverse events reported. He believes there "may very well" be upside to his current $1.5B peak sales estimate by the mid-2020s. The analyst reiterates an Overweight rating on Loxo Oncology with a $200 price target.
09/26/18
STFL
09/26/18
NO CHANGE
Target $217
STFL
Buy
Loxo data not 'transformational,' but keeps inspiring confidence, says Stifel
Stifel analyst Stephen Willey said the incremental follow-up data from Loxo Oncology's (LOXO) LIBRETTO-001 trial isn't "transformational," but it does confirm his confidence in the establishment of a high competitive hurdle for LOXO-292, which he sees being a "best-in-class" and first-to-market asset in a $1B+ market. He remains confident LOXO-292 is the superior asset, but acknowledges the anticipation of Blueprint Medicines' (BPMC) updated BLU-667 data at some point in late-FY18 to early-FY19 could serve as a bit of headwind on Loxo shares nearer to that data release. Willey keeps a Buy rating and $217 price target on Loxo shares.
10/07/18
PIPR
10/07/18
NO CHANGE
Target $200
PIPR
Overweight
Loxo Oncology's 292 remains on top after RET data updates, says Piper Jaffray
Piper Jaffray analyst Tyler Van Buren reiterates an Overweight rating and $200 price target for Loxo Oncology (LOXO) after the company provided an update of the thyroid patients in the Phase I/II study of LOXO-292. The analyst highlights that in the largest patient population the response rate increased from 45% to 59% with three additional patients responding between 9 and 12 months. Blueprint Medicines' (BPMC) competing BLU-667 reported a 49% ORR in a similar patient population and recall that adverse events of hypertension are still a concern, he notes. Van Buren believes that the 667's safety profile could continue to look worse as it continues to administer the drug to patients at higher doses and that treatment discontinuations could increase. Overall, the analyst believes Loxo's 292 appears to be the superior RET inhibitor in development, both in terms of efficacy and safety and could easily become a $1B+ drug.

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FIVE

Five Below

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LBRT

Liberty Oilfield Services

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VNO

Vornado

$67.02

0.77 (1.16%)

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CHKP

Check Point

$120.01

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Conagra Brands

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UNP

Union Pacific

$176.70

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Southern Company

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TSLA

Tesla

$273.25

2.13 (0.79%)

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GLD

SPDR Gold Shares

$120.40

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OSW

OneSpaWorld

$13.77

(0.00%)

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SCHW

Charles Schwab

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OSW

OneSpaWorld

$13.77

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SHLD

Sears

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LB

L Brands

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  • 16

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TSLA

Tesla

$273.25

2.13 (0.79%)

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AMBR

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CYCN

Cyclerion Therapeutics

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ACDVF

Air Canada

$0.00

(0.00%)

, BA

Boeing

$380.02

2.48 (0.66%)

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$0.00

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BA

Boeing

$380.02

2.48 (0.66%)

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