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AVEO

Aveo Pharmaceuticals

$2.03

0.01 (0.50%)

, AZN

AstraZeneca

$38.63

0.22 (0.57%)

07:08
12/12/18
12/12
07:08
12/12/18
07:08

Aveo Oncology announces immuno-oncology clinical collaboration with AstraZeneca

AVEO Oncology (AVEO) announced that it has entered into a clinical collaboration with AstraZeneca (AZN) to evaluate the safety and efficacy of AstraZeneca's IMFINZI, a human monoclonal antibody directed against programmed death-ligand 1, in combination with FOTIVDA, AVEO's oral, once-daily, potent and highly-selective vascular endothelial growth factor receptor tyrosine kinase inhibitor in first-line hepatocellular carcinoma, or liver cancer, in a Phase 1/2 study. AVEO will serve as the study sponsor, with study costs shared equally by both parties and clinical drug supplied by each respective company. The Phase 1 portion of the study is expected to commence in 2019.

AVEO

Aveo Pharmaceuticals

$2.03

0.01 (0.50%)

AZN

AstraZeneca

$38.63

0.22 (0.57%)

AVEO Aveo Pharmaceuticals
$2.03

0.01 (0.50%)

11/06/18
HCWC
11/06/18
NO CHANGE
Target $9
HCWC
Buy
Aveo Pharmaceuticals price target raised to $9 from $6.50 at H.C. Wainwright
H.C. Wainwright analyst Swayampakula Ramakanth raised his price target for Aveo Pharmaceuticals to $9 saying the company announced positive topline results from the Phase 3 TIVO-3 study investigating the use of tivozanib for the treatment of refractory renal cell carcinoma. The analyst views the results as "very promising" and believes tivozanib still has "ample opportunity" to show a superior overall survival benefit. He believes the drug is on track for approval in 2020 and keeps a Buy rating on Aveo Pharmaceuticals.
11/06/18
NATL
11/06/18
DOWNGRADE
NATL
Neutral
Aveo Pharmaceuticals downgraded to Neutral from Buy at National Securities
11/15/18
PIPR
11/15/18
NO CHANGE
Target $5
PIPR
Overweight
Piper Jaffray sees FDA approval of Aveo's tivozanib in 2020
After Aveo Pharmaceuticals announced European partner EUSA is now receiving German reimbursement for tivozanib to treat first-line advanced renal cell carcinoma, Piper Jaffray analyst Edward Tenthoff said he forecasts royalties of $525,000 this year and $3M in 2019. Tenthoff also forecasts FDA approval and a U.S. launch for tivozanib in 2020, projecting initial sales of $32M growing to $218M by 2025. He maintains an Overweight rating and $5 price target on Aveo shares.
11/27/18
HCWC
11/27/18
NO CHANGE
HCWC
Buy
ImmunoGen CFO resignation not based on current role, says H.C. Wainwright
H.C. Wainwright analyst Debjit Chattopadhyay says the resignation of ImmunoGen (IMGN) CFO David Johnston after the executive was found guilty for civil securities fraud has little to do with the execution of his current responsibilities, but a reflection of his tenure with Aveo Pharmaceuticals (AVEO) pharmaceuticals between 2007 and 2012. Given that a potential guilty verdict was always a possibility, the analyst anticipates a potential replacement "in the not so distant future." With ImmunoGen having made "significant strides" over the past five years, and now closer to commercialization with mirvetuximab Phase 3 readout anticipated during the first half of 2019, any potential replacement might come with prior oncology commercialization experience, and might be a better fit with future needs of the company, Chattopadhyay tells investors in a research note titled "Water Under the old AVEO Bridge." He admits, however, that the resignation is publicity ImmunoGen "could have done without." Chattopadhyay keeps a Buy rating on ImmunoGen with an $18 price target.
AZN AstraZeneca
$38.63

0.22 (0.57%)

11/19/18
11/19/18
DOWNGRADE

Hold
AstraZeneca downgraded to Hold from Buy at Investec
11/19/18
BMOC
11/19/18
NO CHANGE
Target $48
BMOC
Outperform
AstraZeneca price target lowered to $48 from $50 at BMO Capital
BMO Capital analyst Alex Arfaei lowered his price target on AstraZeneca to $48 after its announcement on Friday that the Phase 3 MYSTIC trial did not meet its primary endpoints. The analyst adds that while the data also showed Imfinzi as "clearly active", he sees the "incremental benefit of Treme" as highly uncertain. Arfaei keeps his Outperform rating on AstraZeneca however, reducing his probability of success for Imfinzi+Treme in 1L-NSCLC to 20% from 35%, but maintaining a positive outlook on the upcoming NEPTUNE and POSEIDON trials.
11/19/18
11/19/18
DOWNGRADE

On The Fly: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. AstraZeneca (AZN) downgraded to Hold from Buy at Investec. 2. Charles Schwab (SCHW) downgraded to Neutral from Buy at UBS with analyst Brennan Hawken saying while Schwab's business is growing more rapidly than traditional asset managers, there also seems to be "multiple compression on market sensitive revenues given risks to that outlook." 3. Pan American Silver (PAAS) downgraded to Underperform from Neutral at BofA/Merrill with analyst Lawson Winder citing substantial risk assumed from the Tahoe Resources (TAHO) acquisition and the high priced paid. 4. PNC Financial (PNC) downgraded to Market Perform from Outperform at BMO Capital with analyst Lana Chan saying that the stock is approaching her prior $139 per share forecast and sees the company as challenged in gaining market share through expansion given the competition from other Universal banks. 5. Madrigal Pharmaceuticals (MDGL) downgraded to Underperform at Raymond James with analyst Steven Seedhouse saying he expected MGL-3196 Phase 2 data sentiment to worsen exiting AASLD, but that it was exacerbated by the NASH resolution definition informing the seemingly large effect size of 27% versus 6% was not what he expected. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
12/11/18
JEFF
12/11/18
INITIATION
Target $42
JEFF
Hold
AstraZeneca assumed with a Hold at Jefferies
Jefferies analyst Peter Welford assumed coverage of AstraZeneca with a Hold rating and $42 price target. The analyst is positive on the European large-cap Pharma space "as it enters a period of sustained earnings momentum."

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BA

Boeing

$344.09

-25.04 (-6.78%)

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GMVHF

GVC Holdings

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EYE

National Vision

$22.98

-0.94 (-3.93%)

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CI

Cigna

$167.11

2.3 (1.40%)

, HUM

Humana

$289.59

4 (1.40%)

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CI

Cigna

$167.11

2.3 (1.40%)

HUM

Humana

$289.59

4 (1.40%)

UNH

UnitedHealth

$245.59

1.84 (0.75%)

WCG

WellCare

$274.54

0.09 (0.03%)

HNT

Health Net

$0.00

(0.00%)

MOH

Molina Healthcare

$123.03

1.47 (1.21%)

TEVA

Teva

$7.50

-0.26 (-3.35%)

AZN

AstraZeneca

$43.86

-0.25 (-0.57%)

BMY

Bristol-Myers

$53.02

0.6 (1.14%)

LLY

Eli Lilly

$108.68

0.24 (0.22%)

GSK

GlaxoSmithKline

$42.52

0.04 (0.09%)

JNJ

Johnson & Johnson

$127.73

-8.47 (-6.22%)

MRK

Merck

$84.68

0.88 (1.05%)

NVS

Novartis

$86.86

-0.395 (-0.45%)

PFE

Pfizer

$36.46

(0.00%)

RHHBY

Roche

$0.00

(0.00%)

SNY

Sanofi

$46.13

-0.43 (-0.92%)

ANTM

Anthem

$249.55

0.3 (0.12%)

CVS

CVS Health

$66.17

-0.31 (-0.47%)

CNC

Centene

$46.92

-0.28 (-0.59%)

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COP

ConocoPhillips

$53.99

-0.55 (-1.01%)

08:03
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ConocoPhillips stock looking cheap following selloff, Barron's says »

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AMZN

Amazon.com

$1,757.77

-30.07 (-1.68%)

, NFLX

Netflix

$275.40

-17.88 (-6.10%)

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Comcast stacking up better than investors might expect, Barron's says »

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AMZN

Amazon.com

$1,757.77

-30.07 (-1.68%)

NFLX

Netflix

$275.40

-17.88 (-6.10%)

CMCSK

Comcast

$0.00

(0.00%)

CMCSA

Comcast

$45.58

-0.36 (-0.78%)

T

AT&T

$38.46

0.64 (1.69%)

DIS

Disney

$130.91

-1.46 (-1.10%)

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AKS

AK Steel

$2.45

0.055 (2.30%)

, MT

ArcelorMittal

$14.58

0.03 (0.21%)

07:41
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On The Fly
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AKS

AK Steel

$2.45

0.055 (2.30%)

MT

ArcelorMittal

$14.58

0.03 (0.21%)

NUE

Nucor

$51.69

-0.11 (-0.21%)

STLD

Steel Dynamics

$28.71

-0.04 (-0.14%)

TMST

TimkenSteel

$5.42

-0.015 (-0.28%)

X

U.S. Steel

$10.72

0.1 (0.94%)

GM

General Motors

$36.19

-0.01 (-0.03%)

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AAVMY

ABN Amro

$0.00

(0.00%)

, BBVA

Banco Bilbao

$5.38

0.07 (1.32%)

04:55
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Conference/Events
Institute of International Finance to hold annual meeting »

2019 IIF Annual Meeting…

AAVMY

ABN Amro

$0.00

(0.00%)

BBVA

Banco Bilbao

$5.38

0.07 (1.32%)

BCS

Barclays

$8.48

0.11 (1.31%)

BLK

BlackRock

$445.26

-5.56 (-1.23%)

BNPQY

BNP Paribas

$0.00

(0.00%)

C

Citi

$69.76

0.16 (0.23%)

CAIXY

CaixaBank

$0.00

(0.00%)

CIB

Bancolombia

$49.65

0.12 (0.24%)

CS

Credit Suisse

$12.34

0.045 (0.37%)

EV

Eaton Vance

$44.07

-0.49 (-1.10%)

GS

Goldman Sachs

$206.61

0.13 (0.06%)

HSBC

HSBC

$38.72

-0.165 (-0.42%)

JPM

JPMorgan

$120.60

0.21 (0.17%)

MA

MasterCard

$270.90

-5.74 (-2.07%)

MCO

Moody's

$217.41

-1.33 (-0.61%)

MS

Morgan Stanley

$43.70

0.25 (0.58%)

NYT

New York Times

$29.76

0.21 (0.71%)

PYPL

PayPal

$101.25

-2.38 (-2.30%)

RBS

RBS

$6.14

0.205 (3.46%)

RY

Royal Bank of Canada

$81.49

0.38 (0.47%)

SMFG

Sumitomo Mitsui

$6.87

-0.04 (-0.58%)

SPGI

S&P Global

$250.62

-2.15 (-0.85%)

STT

State Street

$63.40

3.69 (6.18%)

UBS

UBS

$11.35

0.09 (0.80%)

V

Visa

$175.83

-2.11 (-1.19%)

ZURVY

Zurich Insurance

$0.00

(0.00%)

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STT

State Street

$63.40

3.69 (6.18%)

20:09
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Upgrade
State Street rating change at Keefe Bruyette »

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SUN

Sunoco

$32.43

0.32 (1.00%)

19:53
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Upgrade
Sunoco rating change at BMO Capital »

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TLF

Tandy Leather

$4.61

(0.00%)

18:24
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Tandy Leather CFO Castillo to step down »

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TLF

Tandy Leather

$4.61

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Tandy Leather says most recent annual report statements not reliable »

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AAPL

Apple

$236.29

0.99 (0.42%)

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U.S. lawmakers request Apple restore HKMapp app in Hong Kong »

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JPM

JPMorgan

$120.60

0.21 (0.17%)

, FB

Facebook

$185.96

-4.435 (-2.33%)

17:59
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JPMorgan CEO says Libra 'a neat idea that will never happen,' Reuters says »

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JPM

JPMorgan

$120.60

0.21 (0.17%)

FB

Facebook

$185.96

-4.435 (-2.33%)

PYPL

PayPal

$101.25

-2.38 (-2.30%)

MA

MasterCard

$270.90

-5.74 (-2.07%)

V

Visa

$175.83

-2.11 (-1.19%)

EBAY

eBay

$38.82

-0.31 (-0.79%)

BKNG

Booking Holdings

$2,012.20

-16.43 (-0.81%)

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GLD

SPDR Gold Shares

$140.47

-0.13 (-0.09%)

17:52
10/18/19
10/18
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17:52
Hot Stocks
SPDR Gold Shares holdings rise to 924.64MT from 918.19MT »

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TECK

Teck Resources

$16.48

0.11 (0.67%)

17:43
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Hot Stocks
Teck Resources gets approval for stock buyback for up to 40M class B shares »

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OSK

Oshkosh

$77.22

0.46 (0.60%)

17:41
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17:41
Hot Stocks
Oshkosh awarded $159.14M Army contract for medium tactical vehicle production »

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OVLY

Oak Valley Bancorp

$16.40

-0.16 (-0.97%)

17:35
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10/18
17:35
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17:35
Earnings
Oak Valley Bancorp reports Q3 EPS 40c vs. 37c last year »

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FTNW

FTE Networks

$0.79

-0.0185 (-2.29%)

17:21
10/18/19
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17:21
Hot Stocks
FTE Networks receives noncompliance notice from NYSE American »

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TNXP

Tonix Pharmaceuticals

$0.45

0.0048 (1.07%)

17:12
10/18/19
10/18
17:12
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17:12
Syndicate
Breaking Syndicate news story on Tonix Pharmaceuticals »

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RLMD

Relmada Therapeutics

$20.18

1.07 (5.60%)

17:10
10/18/19
10/18
17:10
10/18/19
17:10
Syndicate
Breaking Syndicate news story on Relmada Therapeutics »

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16:55
10/18/19
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16:55
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16:55
General news
Breaking General news story  »

Dallas Federal Reserve…

NWSA

News Corp.

$13.48

-0.19 (-1.39%)

, NWS

News Corp

$13.79

-0.11 (-0.79%)

16:51
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16:51
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16:51
Periodicals
Facebook reaches pact with News Corp., others for news section, WSJ says »

News Corp. (NWSA) has…

NWSA

News Corp.

$13.48

-0.19 (-1.39%)

NWS

News Corp

$13.79

-0.11 (-0.79%)

FB

Facebook

$185.96

-4.435 (-2.33%)

NYT

New York Times

$29.76

0.21 (0.71%)

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WAIR

Wesco Aircraft

$11.01

0.01 (0.09%)

16:46
10/18/19
10/18
16:46
10/18/19
16:46
Conference/Events
Wesco Aircraft to host special shareholder meeting »

Special Shareholder…

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FOMX

Foamix

$3.15

-0.09 (-2.78%)

16:41
10/18/19
10/18
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10/18/19
16:41
Hot Stocks
Breaking Hot Stocks news story on Foamix »

Foamix up 7.5% at $3.35…

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