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ALNY

Alnylam

$83.08

2.4 (2.97%)

09:30
01/21/19
01/21
09:30
01/21/19
09:30

Alnylam, Israel's Medison partner to commercialize Onpattro, RNAi portfolio

Alnylam Pharmaceuticals and Israel's Medison Pharma announced an exclusive agreement to commercialize Onpattro as well as other investigational therapeutics under development in the Alnylam RNAi portfolio. "Our partnership with Medison marks an important step in our global commercial expansion and signals our intent to ensure that patients suffering from serious rare diseases have access to our medicines, regardless of location," said Theresa Heggie, SVP and Head of Europe, Middle East and Africa, and Canada, Alnylam Pharmaceuticals. The agreement between Alnylam and Medison includes Onpattro, approved in the European Union in August 2018 for the treatment of hATTR amyloidosis in adults with stage one or stage two polyneuropathy; givosiran, a late-stage investigational RNAi therapeutic for the treatment of acute hepatic porphyria; and lumasiran, a late-stage investigational RNAi therapeutic for the treatment of Primary Hyperoxaluria Type 1. These medicines are not currently approved for use in Israel and givosiran and lumasiran have not yet been approved by any regulatory authority, Alnylam noted.

ALNY Alnylam
$83.08

2.4 (2.97%)

01/15/19
PIPR
01/15/19
NO CHANGE
Target $152
PIPR
Overweight
Alnylam price target lowered to $152 from $160 at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff lowered his price target on Alnylam to $152 to account for dilution after the company announced a 5M share stock offering yesterday. The analyst keeps his Overweight rating on the shares and sees its next potential catalyst in the release of the full Phase III givosiran data this quarter, which he expects to lead to approval of the company's second RNAi around the end of 2019.
01/07/19
PIPR
01/07/19
NO CHANGE
PIPR
Alnylam reports better-than-expected Onpattro revenues, says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff reiterated an Overweight rating and $160 price target on Alnylam Pharmaceuticals after the company reported unaudited Q4 global net revenues for Onpattro in the range of $11M-$12M, above the firm's estimate and Street consensus. Alnylam has not provided FY19 Onpattro sales guidance, but Piper forecasts $81M, citing an expanding European launch and anticipated approval in Japan. The next catalyst will be full Phase III givosiran data this quarter, which Tenthoff expects could lead to approval of Alnylam's second RNAi around the end of 2019.
12/18/18
12/18/18
INITIATION

Fly Intel: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Logitech (LOGI) initiated with an Outperform at Wedbush. 2. Alnylam (ALNY) initiated with a Buy at Guggenheim, while BioMarin (BMRN) was initiated with a Neutral. 3. Tailored Brands (TLRD) initiated with a Buy at B. Riley FBR. 4. Adecogro (AGRO) initiated with a Neutral at Citi. 5. Shopify (SHOP) initiated with an Outperform at Wells Fargo. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
12/17/18
GUGG
12/17/18
INITIATION
Target $105
GUGG
Buy
Alnylam initiated with a Buy at Guggenheim
Guggenheim analyst Whitney Ijem started Alnylam Pharmaceuticals with a Buy rating and $105 price target. The analyst expects the Onpattro launch will go well given the existing pool of identified patients and the drugs's profile versus competitors. Second generation vutrisiran will likely further solidify Alnylam's competitive positioning and expand the market opportunity, Ijem tells investors in a research note.

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