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CRSP

Crispr Therapeutics

$37.21

1.22 (3.39%)

06:36
01/22/19
01/22
06:36
01/22/19
06:36

Crispr Therapeutics downgraded to Sell from Neutral at Citi

Citi analyst Yigal Nochomovitz downgraded Crispr Therapeutics to Sell.

CRSP Crispr Therapeutics
$37.21

1.22 (3.39%)

01/02/19
PIPR
01/02/19
NO CHANGE
Target $75
PIPR
Overweight
Crispr Therapeutics named a top pick for 2019 at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff names Crispr Therapeutics a top pick for 2019 and reiterates an Overweight rating on the shares with a $75 price target. The stock closed the trading day up $1.30 to $29.87. Crispr is developing "revolutionary" CRISPR/Cas-9 technology as a new therapeutic modality with broad ranging applicability, Tenthoff tells investors in a research note. The Phase I/II studies of CTX-001 in transfusion-dependent beta thalassemia and sickle cell disease will report first-in-man data this year potentially curing patients of disease, adds the analyst.
12/20/18
PIPR
12/20/18
NO CHANGE
Target $75
PIPR
Overweight
Piper Jaffray encouraged by enthusiasm for Crispr Therapeutics' CTX-001
Piper Jaffray analyst Edward Tenthoff kept his Overweight rating and $75 price target, saying his interviews with hematologists indicate that the current standard-of-care hydroxyurea is poorly tolerated and offers "a huge opportunity" for emerging therapies. The analyst states that he is encouraged by "early enthusiasm based on the promise of CRISPR/Cas9 in SCD considering the company has yet to present any clinical data on CTX-001."
11/30/18
NEED
11/30/18
INITIATION
Target $62
NEED
Buy
Crispr Therapeutics initiated with a Buy at Needham
Needham analyst Alan Carr initiated CRISPR Therapeutics (CRSP) with a Buy rating and a price target of $62 based on its position as a "leader in gene editing". The analyst notes that the company is "initially focused on ex vivo applications of the technology associated with reduced technical and safety risks", which he believes to hold "substantial value, particularly in immuno-oncology." Carr adds that with Crispr and collaborator Vertex (VRTX) recently launching a clinical development of CTX-001 in Beta Thalassemia and Sickle Cell Disease, he estimates the company to launch these products in the U.S. in 2022 and 2023, respectively.
11/11/18
PIPR
11/11/18
NO CHANGE
Target $75
PIPR
Overweight
Piper Jaffray bullish on Crispr Therapeutics after SITC data
Piper Jaffray analyst Edward Tenthoff notes that Crispr Therapeutics presented a poster at SITC that showed the "impressive" capability of CRISPR/Cas9 to now introduce up to 7 edits to produce an allogeneic CART. The analyst believes the number of edits, unrivaled by other editing modalities, and strong efficiency with 50%-70% rates underscores the robust capabilities offered by CRISPR/Cas9 editing and could diversify the company's CAR-T pipeline in a competitive field. SITC data revealed quadruple-edited cells more potently inhibited tumor growth in vivo versus dual edits, he adds. Tenthoff points out that Crispr Therapeutics expects to initiate a Phase I study on CD19 CAR-T CTX110 in 1H19, with BCMA and CD70 CAR-Ts to follow. First-in-man CTX001 data next year could lead to accelerated approvals by 2021, he contended. The analyst reiterates an Overweight rating and $75 price target on the shares.

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