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SCYX

Scynexis

$0.72

-0.0196 (-2.65%)

16:16
01/30/19
01/30
16:16
01/30/19
16:16

Scynexis reports 'positive' interim Phase 2 results for ibrexafungerp

Scynexis announced positive results from the first interim efficacy analysis of the ongoing FURI study. FURI is a Phase 3 open-label study evaluating oral ibrexafungerp as a salvage treatment in patients with difficult-to-treat mucocutaneous and invasive fungal infections that are refractory to or intolerant of currently available standards of care. Oral ibrexafungerp showed clinical benefits in 17 out of 20 patients, with 11 patients achieving a complete or partial response and six patients a stable disease response. These preliminary results support continued patient enrollment in the FURI study to build toward a future New Drug Application submission and potential approval through the Limited Population Pathway for Antibacterial and Antifungal Drugs. Oral ibrexafungerp was well-tolerated, with the most common treatment-related adverse events being gastrointestinal.

  • 30

    Jan

SCYX Scynexis
$0.72

-0.0196 (-2.65%)

06/27/18
06/27/18
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Zimmer Biomet (ZBH) initiated with an Underperform at Bernstein. 2. Abeona Therapeutics (ABEO) initiated with a Buy at B. Riley FBR. 3. Johnson & Johnson (JNJ) initiated with a Market Perform at Bernstein. 4. T-Mobile (TMUS) initiated with an Overweight at Barclays. 5. Scynexis (SCYX) initiated with a Buy at Maxim. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
07/11/18
NEED
07/11/18
UPGRADE
Target $5
NEED
Buy
Scynexis upgraded to Buy from Hold at Needham
Needham analyst Alan Carr upgraded Scynexis to Buy from Hold and set a $5 price target on the shares.
07/11/18
NEED
07/11/18
UPGRADE
Target $5
NEED
Buy
Scynexis upgraded to Buy at Needham after positive phase 2b data for SCY-078
As reported earlier, Needham analyst Alan Carr upgraded Scynexis (SCYX) to Buy from Hold with a price target of $5 after the company's positive Phase 2b trial results of oral SCY-078 in Vulvovaginal Candidiasis. The analyst notes that the data shows the 1-day 300mg BID SCY-078 is "at least equivalent and likely more effective" than the standard 150mg single dose of fluconazole made by Pfizer (PFE). Carr adds that the gastrointestinal tolerability of SCY-078 is also acceptable, which was a key concern in the earlier Phase 2a trial. The analyst further states that the new valuation accounts for expected commercialization of the drug in VVC amid a likely strong interest in a new oral agent suggested by his ObGyn survey last month.
10/23/18
HCWC
10/23/18
NO CHANGE
Target $4.5
HCWC
Buy
Scynexis shares 'severely' undervalue VVC opportunity, says H.C. Wainwright
Scynexis this morning announced a successful end-of-Phase 2 meeting with the FDA that will allow it to proceed with the planned Phase 3 program in vulvovaginal candidiasis, H.C. Wainwright analyst Oren Livnat tells investors in a research note. The analyst this program is the entire driver of his Scynexis valuation. He keeps a Buy rating on the shares with a $4.50 price target. While Scynexis has had its setbacks, primarily with its previous ibrexafungerp program for hospital-based severe fungal infection, the current approximate $0 enterprise value "severely undervalues" its potential solely in vulvovaginal candidiasis, the analyst contends. Further, Livnat believes Scynexis should have enough cash to get through the first half of 2020.

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