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SYRS

Syros Pharmaceuticals

$6.51

-0.19 (-2.84%)

07:16
02/14/19
02/14
07:16
02/14/19
07:16

Syros Pharmaceuticals assumed with an Outperform at Oppenheimer

Oppenheimer analyst Mark Breidenbach assumed coverage of Syros Pharmaceuticals with an Outperform rating and a $13 price target. The analyst believes the company's lead program, SY-1425, has demonstrated compelling clinical proof-of-concept in a biomarker-defined population of acute myeloid leukemia patients and has an opportunity for approval in multiple therapeutic settings. However, recent changes in the AML competitive landscape, such as the approval of venetoclax, could limit uptake and prolong development timelines relative to previous estimates, he contends. Nonetheless, Breidenbach sees SY-1425 + azacitidine as a promising combination therapy in AML and expects the company to announce updated development plans in early 2019.

SYRS Syros Pharmaceuticals
$6.51

-0.19 (-2.84%)

07/17/18
PIPR
07/17/18
NO CHANGE
Target $28
PIPR
Overweight
Piper reiterates Overweight on Syros after call with oncologists
After hosting a call with two hematologic oncologists to highlight the unmet need to treat myelodysplastic syndromes and acute myeloid leukemia, Piper Jaffray analyst Edward Tenthoff reiterates an Overweight rating on shares of Syros Pharmaceuticals with a $28 price target. The analyst notes the company is conducting a Phase II study for SY-1425 in combination with azacitidine or anti-CD38 antibody Darzalex to treat intermediate to high-risk MDS or AML patients with data likely in Q4. Tenthoff remains confident in Syros' combination strategies in the ongoing study.
11/05/18
ROTH
11/05/18
UPGRADE
ROTH
Buy
Syros Pharmaceuticals upgraded to Buy from Neutral at Roth Capital
11/16/18
PIPR
11/16/18
NO CHANGE
Target $28
PIPR
Overweight
Syros Phase I dose escalation data 'encouraging,' says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff found the Phase I dose escalation data presented by Syros Pharmaceuticals for its CDK7 inhibitor SY-1365 "encouraging." Intravenous SY-1365 was safe and well tolerated with manageable adverse events, Tenthoff tells investors in a research note. The analyst points out that one relapsed ovarian cancer patient achieved partial response with six additional patients with stable disease, bringing the disease control rate to 37% in seven of 19 evaluable patients. He reiterates an Overweight rating on Syros with a $28 price target.

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KRNY

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CPRT

Copart

$53.43

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MESO

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