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ICPT

Intercept

$117.31

6.54 (5.90%)

07:23
02/20/19
02/20
07:23
02/20/19
07:23

Intercept price target raised to $175 from $140 at Oppenheimer

Oppenheimer analyst Jay Olson raised his price target for Intercept to $175 from $140 after top line results from the Phase 3 REGENERATE study of OCA in NASH were statistically significant for Fibrosis Improvement at the 25mg dose but missed statistical significance on NASH Resolution in the primary efficacy analysis population of F2 and F3 patients with a favorable numerical trend for NR. The analyst also increased his estimated probability of success to 90% from 75%, while reiterating an Outperform rating on the shares.

  • 18

    May

ICPT Intercept
$117.31

6.54 (5.90%)

02/19/19
OPCO
02/19/19
NO CHANGE
Target $175
OPCO
Outperform
Intercept price target raised to $175 from $140 at Oppenheimer
Oppenheimer analyst Jay Olson said he is encouraged by the results of Phase 3 REGENERATE study of OCA in NASH and believes that fibrosis improvement should support FDA registration. Following the data report, Olson increased his potential for success odds to 90% from 75% for OCA in NASH and raised his price target on Intercept shares to $175 while keeping an Outperform rating on the stock.
02/19/19
WEDB
02/19/19
NO CHANGE
Target $248
WEDB
Outperform
Intercept price target raised to $248 from $220 at Wedbush
02/19/19
GSCO
02/19/19
NO CHANGE
GSCO
Intercept's Ocaliva likely first FDA approved therapy in NASH, says Goldman Sachs
Goldman Sachs analyst Salveen Richter notes that Intercept reported positive top-line Ocaliva Phase 3 REGENERATE 72-week liver biopsy results in nonalcoholic steatohepatitis. The results confirmed activity of Ocaliva and position the drug to likely be the first FDA approved therapy in NASH, the analyst contends. Richter expects the stock to trade up 50%-plus followed by M&A optionality. Further, the analyst assumes an Ocaliva U.S./EU NASH launch in 2020, and models WW risk-unadjusted peak sales of $3.7B.
02/20/19
PIPR
02/20/19
NO CHANGE
Target $30
PIPR
Overweight
'Underwhelming' Intercept data hurts CymaBay bear thesis, says Piper Jaffray
One of the major constituents of the CymaBay Therapeutics (CBAY) bear thesis has been that pricing for Intercept Pharmaceuticals' (ICPT) Ocaliva would get cut significantly with success in nonalcoholic steatohepatitis and consequently lower the eventual market opportunity for CymaBay's seladelapar in primary biliary cholangitis, Piper Jaffray analyst Tyler Van Buren tells investors in a research note. The analyst, however, believes Intercept's Ocaliva data in NASH yesterday was "underwhelming" as the "fibrosis improvement was mild, no significant effect on NASH was observed, and worrisome safety and tolerability issues remain." Questions regarding the commercial viability of Ocaliva in NASH are now likely to persist, says Van Buren. He now believes Intercept will have to target the most severe patients, "significantly narrowing" the drug's addressable population. This should lead to more stable Ocaliva pricing than many currently assume and keep seladelpar's $750M-plus market opportunity in PBC "largely" intact, contends the analyst. Bottom line is that a major constituent of the CymaBay bear thesis has now been removed, he writes. Van Buren keeps an Overweight rating on the shares with a $30 price target. CymaBay Therapeutics closed yesterday up 34c to $10.29.

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