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MGNX

MacroGenics

$21.98

-0.2 (-0.90%)

, XNCR

Xencor

$33.00

-3.18 (-8.79%)

10:09
02/20/19
02/20
10:09
02/20/19
10:09

Xencor hold supports MacroGenics' 'measured approach,' says H.C. Wainwright

H.C. Wainwright analyst Debjit Chattopadhyay says the partial clinical hold placed on Xencor's (XNCR) XmAb14045 highlights the importance of the "measured approach" MacroGenics (MGNX) has implemented for flotetuzumab. MacroGenics is advancing flotetuzumab, a CD123xCD3 bispecific, for the same indication as mAb14045 and has had a "deliberate approach" to mitigate cytokine release syndrome-related issues, with some "compelling data" in refractory acute myeloid leukemia patients, Chattopadhyay tells investors in a research note. He keeps a Buy rating on MacroGenics with a $39 price target. The stock in early trading is down 32c to $21.83. Xencor is down 6% to $33.76.

MGNX

MacroGenics

$21.98

-0.2 (-0.90%)

XNCR

Xencor

$33.00

-3.18 (-8.79%)

  • 25

    Feb

  • 27

    Feb

MGNX MacroGenics
$21.98

-0.2 (-0.90%)

02/07/19
SBSH
02/07/19
UPGRADE
SBSH
Buy
Citi double upgrades MacroGenics to Buy from Sell even after 130% stock rally
Citi analyst Yigal Nochomovitz double upgraded MacroGenics (MGNX) to Buy from Sell and raised his price target for the shares to $39 from $10. The stock closed yesterday up 130%, or $14.49, to $25.60. Following yesterday's data, the analyst raised his probability of success estimate to 70% from 50% for enoblituzumab in head and neck squamous cell carcinoma and non-small cell lung cancer. Additional Phase 1 readouts in 2019 should provide further stock momentum for MacroGenics, Nochomovitz tells investors in a research note. The analyst also sees MacroGenics as positive for Zai Lab (ZLAB). The Sophia data go a long way to validate Zai's choice of partner in MacroGenics, says the analyst.
02/07/19
02/07/19
DOWNGRADE
Target $26

Neutral
MacroGenics downgraded to Neutral on 'baked in' approval at Wedbush
As previously reported, Wedbush analyst David Nierengarten downgraded MacroGenics to Neutral from Outperform, while raising his price target on the shares to $26 from $20, following positive topline results from the pivotal Phase 3 SOPHIA trial evaluating margetuximab in 3/4L HER2-positive metastatic breast cancer. Overall, the topline readout met Nierengarten's cautiously optimistic expectations for a statistically significant increase in PFS that would warrant BLA submission in 2H19 and subsequent approval. The analyst argued that the current stock reaction approaches his increased and already de-risked valuation.
02/07/19
RHCO
02/07/19
NO CHANGE
Target $40
RHCO
Buy
MacroGenics price target raised to $40 from $28 at SunTrust
SunTrust analyst Peter Lawson raised his price target on MacroGenics to $40 and kept his Buy rating after the company announced "very encouraging results from pivotal Phase 3 study evaluating marge plus chemo in HER2+ breast cancer". The analyst notes that he has raised his probability of success and penetration estimates for the program to 69% and $670M in peak sales by 2025 respectively.
02/07/19
02/07/19
UPGRADE

Fly Intel: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Saia (SAIA) upgraded to Buy from Hold at Deutsche Bank with analyst Amit Mehrotra saying after meeting with management, he is incrementally more confident in Saia's ability to generate double-digit revenue growth this year. 2. Guess (GES) upgraded to Buy from Hold at Jefferies with analyst Janine Stichter saying the recent pullback in the stock puts the company's multiple below its historical average and peers. 3. Spirit Airlines (SAVE) upgraded to Buy from Neutral at Goldman Sachs with analyst Catherine O'Brien saying she expects passenger revenue trends for the company in the first half of the year to be stronger than previously anticipated. 4. MacroGenics (MGNX) upgraded to Buy from Sell at Citi with analyst Yigal Nochomovitz saying additional Phase 1 readouts in 2019 should provide further stock momentum for MacroGenics. 5. Cognizant (CTSH) upgraded to Outperform from Market Perform at BMO Capital with analyst Keith Bachman citing the company's FY19 revenue growth outlook and a positive management transition. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
XNCR Xencor
$33.00

-3.18 (-8.79%)

09/10/18
BTIG
09/10/18
INITIATION
Target $56
BTIG
Buy
Xencor assumed with a Buy at BTIG
BTIG analyst Thomas Shrader assumed Xencor with a Buy rating and a price target of $56, saying the company offers "multiple proprietary techniques" and a "compelling internal pipeline". The analyst further notes that two of its "high quality" partnerships may soon pay royalties, adding that he is positive on Xencor's "XmAb5871 developed in IgG4-related disease and lupus mostly for dosing flexibility". Shrader contends that while the stock is "not cheap", its track and growth prospects are sound.
10/15/18
PIPR
10/15/18
NO CHANGE
PIPR
Piper lists names to own in Biopharma after recent selloff
Piper Jaffray's biopharma analyst team highlighted names to own in the Biopharma sector following the recent selloff of the broader market. The firm's ideas include: Adamas Pharmaceuticals (ADMS), Agios Pharmaceuticals (AGIO), Agios Pharmaceuticals (ALNY), Alexion (ALXN), Bluebird Bio (BLUE), BioMarin (BMRN), CymaBay (CBAY), Crispr Therapeutics (CRSP), Global Blood Therapeutics (GBT), Horizon Pharma (HZNP), Jazz Pharmaceuticals (JAZZ), Ocular Therapeutix (OCUL), Rigel Pharmaceuticals (RIGL) and Xencor (XNCR).
01/07/19
PIPR
01/07/19
NO CHANGE
PIPR
Xencor regaining XmAb13676 rights a 'significant positive,' says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff reiterated an Overweight rating and $52 price target on Xencor (XNCR) after Novartis (NVS) returned full rights of XmAb13676 to Xencor, which the analyst views as a "significant positive." Tenthoff also noted that Novartis continues to co-develop XmAb14045, with Xencor retaining U.S. rights.
02/05/19
PIPR
02/05/19
NO CHANGE
PIPR
Piper Jaffray reiterates Overweight rating on Xencor after Genentech deal
Piper Jaffray analyst Edward Tenthoff reiterated an Overweight rating and $52 price target on Xencor, after the company partnered with Genentech to develop IL-15 targeted cytokine therapies, including XmAb24306. The analyst noted that Xencor will receive $120M upfront, and that the company is also eligible for $160M in XmAb24306-related milestones and $180M in milestones for each new IL-15 candidate. Tenthoff also noted that Xencor will have the right to co-promote in the U.S. and is eligible to receive 45% share of net profits sales.

TODAY'S FREE FLY STORIES

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, DDOG

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PG

Procter & Gamble

$122.22

0.37 (0.30%)

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-0.62 (-1.14%)

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KO

Coca-Cola

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PepsiCo

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CL

Colgate-Palmolive

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0.01 (0.01%)

KMB

Kimberly-Clark

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0.9 (0.67%)

K

Kellogg

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0.07 (0.11%)

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CMCSA

Comcast

$46.36

-0.32 (-0.69%)

, CMCSK

Comcast

$0.00

(0.00%)

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CMCSA

Comcast

$46.36

-0.32 (-0.69%)

CMCSK

Comcast

$0.00

(0.00%)

DAL

Delta Air Lines

$58.63

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FANG

Diamondback Energy

$96.90

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EHC

Encompass Health

$64.41

-0.01 (-0.02%)

FB

Facebook

$189.88

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JNJ

Johnson & Johnson

$131.73

1.75 (1.35%)

MSFT

Microsoft

$139.34

-1.74 (-1.23%)

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YUM

Yum! Brands

$112.31

-1.83 (-1.60%)

, MCD

McDonald's

$209.44

-1.12 (-0.53%)

08:05
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Despite a surge in second…

YUM

Yum! Brands

$112.31

-1.83 (-1.60%)

MCD

McDonald's

$209.44

-1.12 (-0.53%)

CMG

Chipotle

$835.17

3.67 (0.44%)

CBRL

Cracker Barrel

$166.12

-0.23 (-0.14%)

WEN

Wendy's

$20.77

0.22 (1.07%)

QSR

Restaurant Brands

$72.64

-1.24 (-1.68%)

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SFTBF

SoftBank

$0.00

(0.00%)

, SFTBY

SoftBank

$0.00

(0.00%)

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Periodicals
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Investors seem convinced…

SFTBF

SoftBank

$0.00

(0.00%)

SFTBY

SoftBank

$0.00

(0.00%)

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REAL

RealReal

$17.00

0.21 (1.25%)

07:57
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07:57
Periodicals
RealReal among year's more under-the-radar IPOs, Barron's says »

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CVS

CVS Health

$64.28

0.65 (1.02%)

, WAB

Wabtec

$74.01

0.26 (0.35%)

07:48
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Periodicals
Opioid crisis could hurt investors, Barron's says »

Opioid lawsuits have…

CVS

CVS Health

$64.28

0.65 (1.02%)

WAB

Wabtec

$74.01

0.26 (0.35%)

ABC

AmerisourceBergen

$85.13

0.475 (0.56%)

CAH

Cardinal Health

$47.89

-0.14 (-0.29%)

MCK

McKesson

$146.83

1.06 (0.73%)

MYL

Mylan

$21.01

0.03 (0.14%)

AMRX

Amneal Pharmaceuticals

$3.34

0.21 (6.71%)

ABT

Abbott

$83.56

0.35 (0.42%)

MNK

Mallinckrodt

$2.46

0.01 (0.41%)

ENDP

Endo

$3.48

0.115 (3.42%)

TEVA

Teva

$7.44

-0.08 (-1.06%)

JNJ

Johnson & Johnson

$131.73

1.75 (1.35%)

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DDAIF

Daimler AG

$0.00

(0.00%)

, FCAU

Fiat Chrysler

$13.52

-0.11 (-0.81%)

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Catch up on the top…

DDAIF

Daimler AG

$0.00

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FCAU

Fiat Chrysler

$13.52

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F

Ford

$9.16

0.06 (0.66%)

GM

General Motors

$37.37

-0.41 (-1.09%)

HMC

Honda

$26.68

0.03 (0.11%)

NSANY

Nissan

$0.00

(0.00%)

TSLA

Tesla

$240.62

-5.89 (-2.39%)

TM

Toyota

$136.72

0.12 (0.09%)

VWAGY

Volkswagen

$0.00

(0.00%)

FB

Facebook

$189.88

-0.27 (-0.14%)

AGU

Agrium

$0.00

(0.00%)

ANDE

Andersons

$26.28

-0.56 (-2.09%)

ADM

Archer Daniels

$40.94

0.05 (0.12%)

BG

Bunge

$55.91

-0.26 (-0.46%)

CF

CF Industries

$49.28

-0.76 (-1.52%)

CMP

Compass Minerals

$56.29

-1.765 (-3.04%)

IPI

Intrepid Potash

$3.43

0.01 (0.29%)

POT

Potash

$0.00

(0.00%)

SYT

Syngenta

$0.00

(0.00%)

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UPS

UPS

$120.71

1.61 (1.35%)

21:22
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DIS

Disney

$132.18

-1.14 (-0.86%)

, T

AT&T

$37.92

0.78 (2.10%)

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DIS

Disney

$132.18

-1.14 (-0.86%)

T

AT&T

$37.92

0.78 (2.10%)

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BA

Boeing

$379.33

-5.28 (-1.37%)

18:15
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MCF

Contango Oil & Gas

$1.71

-0.07 (-3.93%)

17:58
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09/20
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Karlin Asset Management reports 11.4% passive stake in Contango Oil & Gas »

Karlin Asset Management…

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GLD

SPDR Gold Shares

$142.97

1.68 (1.19%)

17:41
09/20/19
09/20
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17:41
Hot Stocks
SPDR Gold Shares holdings rise to 894.15MT from 883.60MT »

This is the highest level…

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VXRT

Vaxart

$0.58

-0.0307 (-5.03%)

17:37
09/20/19
09/20
17:37
09/20/19
17:37
Syndicate
Vaxart files to sell 15.6M shares of common stock »

H.C. Wainwright acted as…

03/08/13
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AAPL

Apple

$217.69

-3.22 (-1.46%)

17:34
09/20/19
09/20
17:34
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17:34
Periodicals
Apple given tariff exclusion on certain Mac Pro parts, Bloomberg says »

Apple has received U.S.…

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IIVI

II-VI

$39.05

-0.5 (-1.26%)

, CPE

Callon Petroleum

$4.53

-0.015 (-0.33%)

17:31
09/20/19
09/20
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17:31
Hot Stocks
II-VI to enter S&P 400; Callon Petroleum, PriceSmart to enter S&P SmallCap600 »

S&P SmallCap 600…

IIVI

II-VI

$39.05

-0.5 (-1.26%)

CPE

Callon Petroleum

$4.53

-0.015 (-0.33%)

PSMT

PriceSmart

$60.29

-0.39 (-0.64%)

FNSR

Finisar

$24.31

1.25 (5.42%)

03/08/13
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NVR

NVR

$3,632.55

-30.45 (-0.83%)

, JEF

Jefferies Financial Group

$19.47

-0.19 (-0.97%)

17:26
09/20/19
09/20
17:26
09/20/19
17:26
Hot Stocks
NVR to replace Jefferies Financial Group in the S&P 500 at open on September 26 »

NVR (NVR) will replace…

NVR

NVR

$3,632.55

-30.45 (-0.83%)

JEF

Jefferies Financial Group

$19.47

-0.19 (-0.97%)

SPB

Spectrum Brands

$49.66

-1.395 (-2.73%)

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NOC

Northrop Grumman

$368.25

-7.45 (-1.98%)

17:24
09/20/19
09/20
17:24
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17:24
Hot Stocks
Northrop Grumman subsidiary awarded $1.12B Missile Defense Agency contract »

Orbital Sciences, or OSC,…

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PSMT

PriceSmart

$60.29

-0.39 (-0.64%)

, FNSR

Finisar

$24.31

1.25 (5.42%)

17:23
09/20/19
09/20
17:23
09/20/19
17:23
Hot Stocks
Breaking Hot Stocks news story on PriceSmart, Finisar »

PriceSmart to replace…

PSMT

PriceSmart

$60.29

-0.39 (-0.64%)

FNSR

Finisar

$24.31

1.25 (5.42%)

03/08/13
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  • 30

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IIVI

II-VI

$39.05

-0.5 (-1.26%)

, CPE

Callon Petroleum

$4.53

-0.015 (-0.33%)

17:22
09/20/19
09/20
17:22
09/20/19
17:22
Hot Stocks
Breaking Hot Stocks news story on II-VI, Callon Petroleum »

II-VI to replace Callon…

IIVI

II-VI

$39.05

-0.5 (-1.26%)

CPE

Callon Petroleum

$4.53

-0.015 (-0.33%)

03/08/13
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NVR

NVR

$3,632.55

-30.45 (-0.83%)

17:20
09/20/19
09/20
17:20
09/20/19
17:20
Hot Stocks
Breaking Hot Stocks news story on NVR »

NVR to replace Jefferies…

03/08/13
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NHYDY

Norsk Hydro

$0.00

(0.00%)

17:12
09/20/19
09/20
17:12
09/20/19
17:12
Hot Stocks
Norsk Hydro discloses federal court in Brazil lifts embargo on Alunortes »

The Federal Court in…

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RESN

Resonant

$3.05

0.02 (0.66%)

17:03
09/20/19
09/20
17:03
09/20/19
17:03
Conference/Events
Resonant participates in a conference call with Loop Capital »

Semiconductor Analysts…

03/08/13
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03/06/13
Citigroup
03/06/13
Barclays

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NINE

Nine Energy Services

$6.73

-0.33 (-4.67%)

17:02
09/20/19
09/20
17:02
09/20/19
17:02
Syndicate
Breaking Syndicate news story on Nine Energy Services »

Nine Energy Services…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

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ATOM

Atomera

$3.70

0.17 (4.82%)

17:00
09/20/19
09/20
17:00
09/20/19
17:00
Conference/Events
Atomera participates in a conference call with Loop Capital »

Semiconductor Analysts…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

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