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IONS

Ionis Pharmaceuticals

$80.53

0.25 (0.31%)

07:51
03/22/19
03/22
07:51
03/22/19
07:51

Wells reiterates Outperform on Ionis after 'positive' protocol amendment

Wells Fargo analyst Jim Birchenough reiterates an Outperform rating on Ionis Pharmaceuticals following the "positive" Phase 3 protocol amendment for its Roche-partnered Huntington's program for IONIS-HTT-Rx and introduction of more convenient monthly dosing. Less frequent dosing should support more rapid enrollment in the Phase 3 study, Birchenough tells investors in a research note. He believes the timelines for a potential accelerated approval filing on Phase 1 data is intact with an expected FDA meeting by the end of 2019. The analyst sees "significant upside potential" for Ionis shares and maintains a $106 price target.

  • 01

    Apr

IONS Ionis Pharmaceuticals
$80.53

0.25 (0.31%)

03/01/19
PIPR
03/01/19
NO CHANGE
Target $63
PIPR
Overweight
Ionis positive CHMP opinion for Waylivra a surprise, says Piper Jaffray
Given the prior Waylivra Complete Response Letter issued by the FDA, the positive Committee for Medicinal Products for Human Use opinion announced this morning was a surprise to many, Piper Jaffray analyst Tyler Van Buren tells investors in a research note. The analyst anticipates a European Medicines Agency approval in the coming months and models $150M in European Waylivra sales by the late 2020s "with minimal increase in long-term operating spending." As a result, the analyst boosted his price target for Ionis Pharmaceuticals to $63 from $60 while keeping a Neutral rating on the shares.
02/28/19
BMOC
02/28/19
NO CHANGE
Target $82
BMOC
Outperform
Ionis Pharmaceuticals price target raised to $82 from $70 at BMO Capital
BMO Capital analyst Do Kim raised his price target on Ionis Pharmaceuticals to $82 and kept his Outperform rating after its better than expected Q4 results. The analyst is also raising his FY19 and FY20 EPS targets by 28c and 13c to $1.59 and $2.19 respectively on expectations of lower R&D expense projections, adding that more "upside could come from Tegsedi quarterly beats, potential Waylivra refiling, and visibility into an accelerated path for Huntington's".
02/28/19
PIPR
02/28/19
NO CHANGE
Target $60
PIPR
Neutral
Ionis Pharmaceuticals price target raised to $60 from $50 at Piper Jaffray
Piper Jaffray analyst Tyler Van Buren raised his price target for Ionis Pharmaceuticals to $60 citing a good first quarter for Tegsedi. While early, the $2.2M in sales reported for Tegsedi in the first partial quarter was a surprise to many, compares well to the $0.5M reported in the first Onpattro quarter, and caused the shares to be up significantly yesterday, Van Buren tells investors in a research note. The analyst, however, keeps a Neutral rating on Ionis due to valuation.
12/17/18
NEED
12/17/18
NO CHANGE
Target $82
NEED
Buy
Needham names Ionis a top 2019 pick, boosts target to $82
Needham analyst Chad Messer raised his price target for Ionis Pharmaceuticals to $82 from $67 and named the stock a top pick for 2019. Unlike most other biotech companies, Ionis has been executing on a "perennial innovative pipeline while generating sustainable and growing profits," Messer tells investors in a research note. The company has already produced one blockbuster drug with Spinraza and is in the midst of launching a second potential blockbuster Tegsedim, says the analyst. Further, he points out that four additional programs of the company will reach pivotal trials in 2019. Messer keeps a Buy rating on Ionis Pharmaceuticals.

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