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DARE

Dare Bioscience

$1.33 /

-0.16 (-10.74%)

08:38
04/08/19
04/08
08:38
04/08/19
08:38

Dare Bioscience announces publication of DARE-HRT1 data

Dare Bioscience announced the article entitled "Pharmacokinetics and tolerability of a novel 17ss-estradiol and progesterone intravaginal ring in sheep" was published online in the Journal of Pharmaceutical Sciences. The goal of the research described in the article was to characterize the release, pharmacokinetics and local tolerability of DARE-HRT1, a potential and novel hormone replacement therapy. DARE-HRT1, an ethylene-vinyl acetate intravaginal ring, or IVR, drug delivery technology delivering 17ss-estradiol and progesterone, was evaluated in drug-naive ovariectomized female Dorset crossbred sheep. DARE-HRT1 is being developed as a combination bio-identical estradiol and bio-identical progesterone IVR for hormone replacement therapy, or HRT, to treat vasomotor symptoms, commonly called hot-flashes and associated with menopause, as part of an HRT regimen. The North American Menopause Society consensus statement supports HRT in peri- and post-menopausal women and recommends administering both estrogen to reduce symptoms and progesterone to prevent thickening of the uterine wall, in addition to recommending a non-oral route over an oral route. The design of DARE-HRT1 is intended to allow the continuous delivery of bio-identical estradiol and bio-identical progesterone in one IVR over a 28- day period. In a separate study of 44 healthy female post-menopausal women, more than 90% said an IVR would make taking their medications easier and 88% reported they would be very likely to use an IVR for a condition related to Women's Health.

DARE Dare Bioscience
$1.33 /

-0.16 (-10.74%)

08/17/18
On The Fly: Top five analyst initiations
08/17/18 Maxim
Dare Bioscience initiated with a Buy at Maxim
08/17/18 Maxim
Dare Bioscience initiated with a Buy at Maxim
05/16/18 Roth Capital
Dare Bioscience initiated with a Buy at Roth Capital

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