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RHHBY

Roche

$0.00

(0.00%)

07:23
05/07/19
05/07
07:23
05/07/19
07:23

Genentech presents data from FIREFISH and SUNFISH studies

Genentech, a member of the Roche Group, announced new data from the dose-finding Part 1 of the pivotal FIREFISH trial showing infants with Type 1 spinal muscular atrophy achieved key motor milestones after one year of treatment with investigational risdiplam. Among the infants who received the dose selected for the confirmatory Part 2 of the study, seven were able to sit without support for at least 5 seconds, assessed by the Gross Motor Scale of the Bayley Scales of Infant and Toddler Development - Third Edition. In addition, 11 infants were able to sit (with or without support) while nine achieved upright head control after 12 months of treatment as assessed by the Hammersmith Infant Neurological Examination Module 2. Finally, one infant achieved the milestone of standing by this 12-month time point. The confirmatory Part 2 portions of the SUNFISH and FIREFISH studies have completed enrollment and will conduct their primary efficacy analyses in Q4 2019 and Q1 2020, respectively.

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RHHBY Roche
$0.00

(0.00%)

04/10/19
MSCO
04/10/19
DOWNGRADE
MSCO
Underweight
Novartis downgraded to Underweight from Equal Weight at Morgan Stanley
Morgan Stanley analyst Mark Purcell downgraded Novartis (NVS) to Underweight from Equal Weight and lowered his price target for the shares to 80 francs. The spinoff of Alcon will put more attention on the generics risk Novartis faces in its pharma business, Purcell tells investors in a research note. The analyst believes this generic pressure is not priced into shares of Novartis. His top pick remains Roche (RHHBY).
04/17/19
WELS
04/17/19
NO CHANGE
WELS
Wells says Ionis weakness on Roche Huntington's update a buying opportunity
04/17/19
WELS
04/17/19
NO CHANGE
WELS
Outperform
Ionis pullback on Roche update a buying opportunity, says Wells Fargo
Wells Fargo analyst Jim Birchenough reiterated his Outperform rating on Ionis Pharmaceuticals (IONS) following an update today from partner Roche (RHHBY) on its HTT-ASO program for Huntington's disease, stating that he believes the update continues to support potential for accelerated approval filing pending efficacy data that should be updated by year end. When asked during its earnings call about the specific filing strategy of using phase 1 OLE data in comparison to the natural history data, Roche made no comment beyond reiterating that the company will get data, share data with regulators, and work on the fastest way to bring the therapy to patients, said Birchenough. The analyst, who recommends buying Ionis on weakness, added that Roche noted that the company has had initial promising discussion with regulators.
04/22/19
BMOC
04/22/19
NO CHANGE
Target $96
BMOC
Outperform
Ionis Pharmaceuticals price target raised to $96 from $82 at BMO Capital
BMO Capital analyst Do Kim raised his price target on Ionis Pharmaceuticals (IONS) to $96 and kept his outperform rating after including the risk-adjusted royalties for HTT-Rx in his model as part of the update on its partnership with Roche (RHHBY) disclosed last month. The analyst notes that the stock price has started to reflect the company's Huntington's disease opportunity based on the "potential for an accelerated path with Phase 2 data" and believes that his HTT-Rx projections could prove to be "conservative".

TODAY'S FREE FLY STORIES

DSNKY

Daiichi Sankyo

$0.00

(0.00%)

18:39
05/22/19
05/22
18:39
05/22/19
18:39
Periodicals
Breaking Periodicals news story on Daiichi Sankyo »

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SPOT

Spotify

$127.10

-5.06 (-3.83%)

18:27
05/22/19
05/22
18:27
05/22/19
18:27
Periodicals
Spotify resets some users' passwords over 'suspicious activity,' TechCrunch says »

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IDXX

Idexx Laboratories

$250.45

1.24 (0.50%)

18:20
05/22/19
05/22
18:20
05/22/19
18:20
Hot Stocks
Idexx Laboratories CEO: We're at the beginning of our runway for growth »

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OMC

Omnicom

$79.79

-0.3 (-0.37%)

18:15
05/22/19
05/22
18:15
05/22/19
18:15
Hot Stocks
Omnicom CEO sells 60.5K shares of common stock »

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BSX

Boston Scientific

$37.74

0.04 (0.11%)

18:12
05/22/19
05/22
18:12
05/22/19
18:12
Hot Stocks
Boston Scientific initiates trial of WATCHMAN FLX appendage closure platform »

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CTRP

Ctrip

$37.63

-0.24 (-0.63%)

18:03
05/22/19
05/22
18:03
05/22/19
18:03
Hot Stocks
Ctrip reports Q1 gross margin 79% vs. 82% a year ago »

Remained consistent with…

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CTRP

Ctrip

$37.63

-0.24 (-0.63%)

18:02
05/22/19
05/22
18:02
05/22/19
18:02
Earnings
Breaking Earnings news story on Ctrip »

Ctrip sees Q2 net revenue…

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CTRP

Ctrip

$37.63

-0.24 (-0.63%)

18:01
05/22/19
05/22
18:01
05/22/19
18:01
Earnings
Ctrip reports Q1 adjusted EPS 44c, consensus 24c »

Reports Q1 revenue $1.2B,…

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CE

Celanese

$100.10

-0.18 (-0.18%)

18:01
05/22/19
05/22
18:01
05/22/19
18:01
Hot Stocks
Celanese announces acetyls product price increases »

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XRAY

Dentsply Sirona

$54.64

-0.25 (-0.46%)

17:57
05/22/19
05/22
17:57
05/22/19
17:57
Hot Stocks
Dentsply Sirona CFO Alexos to leave company in connection with relocation »

In a regulatory filing,…

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  • 22

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SIM

Grupo Simec

$9.23

(0.00%)

17:55
05/22/19
05/22
17:55
05/22/19
17:55
Hot Stocks
Grupo Simec receives noncompliance notification from NYSE »

Grupo Simec announced…

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CPRT

Copart

$64.78

-1.12 (-1.70%)

17:51
05/22/19
05/22
17:51
05/22/19
17:51
Earnings
Copart reports Q3 adjusted EPS 66c, consensus 62c »

Reports Q3 revenue…

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NVS

Novartis

$83.94

1.555 (1.89%)

17:51
05/22/19
05/22
17:51
05/22/19
17:51
Periodicals
Novartis CEO sees Zolgensma price 'far lower' than $4M-$5M range, Reuters says »

Novartis CEO Vas…

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PCG

PG&E

$19.00

0.55 (2.98%)

17:45
05/22/19
05/22
17:45
05/22/19
17:45
Periodicals
PG&E to remain in control of bankruptcy until September 29, WSJ reports »

PG&E will remain in…

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  • 21

    Jun

OBLN

Obalon Therapeutics

$1.24

0.842 (211.56%)

17:41
05/22/19
05/22
17:41
05/22/19
17:41
Hot Stocks
Obalon Therapeutics discloses resignation of CEO »

In a regulatory 8-K…

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GVA

Granite Construction

$41.37

-0.09 (-0.22%)

17:39
05/22/19
05/22
17:39
05/22/19
17:39
Hot Stocks
Granite Construction acquires additional trenchless rehabilitation assets »

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  • 06

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NVCN

Neovasc

$0.48

-0.0023 (-0.48%)

17:36
05/22/19
05/22
17:36
05/22/19
17:36
Hot Stocks
Neovasc discloses International Journal of Cardiology review of Neovasc Reducer »

Neovasc announced that…

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SPX

S&P 500

$0.00

(0.00%)

, SPY

SPDR S&P 500 ETF Trust

$285.61

-0.89 (-0.31%)

17:36
05/22/19
05/22
17:36
05/22/19
17:36
Periodicals
Pentagon mulls request to send 5,000 U.S. troops to Middle East, Reuters says »

The U.S. Department of…

SPX

S&P 500

$0.00

(0.00%)

SPY

SPDR S&P 500 ETF Trust

$285.61

-0.89 (-0.31%)

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POOL

Pool Corp.

$183.36

-0.52 (-0.28%)

17:35
05/22/19
05/22
17:35
05/22/19
17:35
Hot Stocks
Pool Corp. Chairman John Stokely sells almost $2M in company shares »

Pool Corp. Chairman John…

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RTN

Raytheon

$180.57

-2.05 (-1.12%)

17:35
05/22/19
05/22
17:35
05/22/19
17:35
Hot Stocks
Raytheon awarded $151.47M Navy contract for AIM-9X missile sustainment »

Raytheon has been awarded…

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ESV

Ensco Rowan

$10.01

-0.365 (-3.52%)

17:31
05/22/19
05/22
17:31
05/22/19
17:31
Hot Stocks
Ensco Rowan says will not pay a regular quarterly cash dividend »

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AMGN

Amgen

$171.29

1.67 (0.98%)

, GILD

Gilead

$66.51

-0.01 (-0.02%)

17:30
05/22/19
05/22
17:30
05/22/19
17:30
Upgrade
Amgen, Gilead, Alexion, Vertex, BioMarin, Biogen, Regeneron rating change  »

Citi assumes coverage of…

AMGN

Amgen

$171.29

1.67 (0.98%)

GILD

Gilead

$66.51

-0.01 (-0.02%)

ALXN

Alexion

$127.47

-1.33 (-1.03%)

VRTX

Vertex

$172.37

3.22 (1.90%)

BMRN

BioMarin

$87.80

0.33 (0.38%)

BIIB

Biogen

$234.98

2.04 (0.88%)

REGN

Regeneron

$320.00

10.19 (3.29%)

03/08/13
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BBX

BBX Capital

$4.95

-0.06 (-1.20%)

, BXG

Bluegreen Vacations

$14.91

-0.2 (-1.32%)

17:24
05/22/19
05/22
17:24
05/22/19
17:24
Hot Stocks
BBX Capital says will not proceed with merger with Bluegreen Vacations »

BBX Capital (BBX)…

BBX

BBX Capital

$4.95

-0.06 (-1.20%)

BXG

Bluegreen Vacations

$14.91

-0.2 (-1.32%)

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RTN

Raytheon

$180.57

-2.05 (-1.12%)

17:21
05/22/19
05/22
17:21
05/22/19
17:21
Hot Stocks
Raytheon awarded $234.64M Navy contract »

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  • 30

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WEX

Wex

$203.30

-1.56 (-0.76%)

17:20
05/22/19
05/22
17:20
05/22/19
17:20
Hot Stocks
Wex CEO sells 5K shares of common stock »

In a regulatory filing,…

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