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AVRO

Avrobio

$14.35

-1.2 (-7.72%)

04:59
06/27/19
06/27
04:59
06/27/19
04:59

Mizuho starts Avrobio with Buy rating, $28 price target

Mizuho analyst Difei Yang last night initiated coverage of Avrobio with a Buy rating and $28 price target. Avrobio is a gene therapy company using a proprietary ex-vivo lentiviral vector platform to address unmet needs in lysosomal storage diseases, a $4B total addressable market, Yang tells investors in a research note. The analyst believes available clinical data in Fabry disease has shown "encouraging" results.

  • 09

    Sep

AVRO Avrobio
$14.35

-1.2 (-7.72%)

11/27/18
LEER
11/27/18
INITIATION
LEER
Leerink initiates select Genetic Medicine names on increasing regulatory clarity
Leerink analyst Mani Foroohar initiated select Genetic Medicine stocks, stating that the field is "is rich with companies developing drugs" to treat rare diseases and that he is increasingly more bullish on "innovation velocity and increasing regulatory clarity in the sector. Based on his "balanced view of pricing dynamics", the analyst issues an Outperform rating on Wave Life Sciences (WVE), Rocket Pharmaceuticals (RCKT), Intellia Therapeutics (NTLA), Eidos Therapeutics (EIDX), Dicerna (DRNA) and Bluebird Bio (BLUE). The analyst likes Wave Life Sciences as a pure play on Oligotherapeutics and its stereopure chemistry platform as a differentiated approach to oligo drug design. Foroohar is positive on Rocket Pharma's lead assets in gene therapies for Fanconi Anemia and Leukocyte Adhesion Deficiency-I "which will likely be the company's first potential approved product." The analyst is positive on Intellia Therapeutics' "robust balance sheet to support development, trading at a material discount to closest comps peers". For Eidos, the analyst cites the prospects of its drug candidate for TTR amyloidosis currently in a placebo-controlled Phase 2 study that may offer a competitive profile relative to Pfizer's (PFE) tafamidis. For Dicerna, Foroohar notes that its DCR-PHXC "is an RNAi therapeutic that targets lactate dehydrogenase A for the treatment of all subtypes of Primary Hyperoxaluria vs. competitor Alnylam's (ALNY) lumasiran, which only treats PH Type 1. For Bluebird Bio, the analyst is positive on its position as a "leader in ex vivo gene therapy, with four programs with visibility towards near-term regulatory approval". Foroohar initiates Avrobio (AVRO), Alnylam (ALNY), and Ionis Pharmaceuticals (IONS) with Market Perform rating based on competitive launches for their products along with "mixed" early signs of their results. The analyst also rates Regenxbio (RGNX) at underperform, saying that its "current valuation more than accounts for robust royalty streams from sales in spinal muscular atrophy" and other partnered assets.
01/17/19
LEER
01/17/19
NO CHANGE
Target $19
LEER
Market Perform
Avrobio price target lowered to $19 from $27 at Leerink
Leerink analyst Mani Foroohar lowered his price target for Avrobio to $19 from $27, while reiterating a Market Perform rating on the shares. While the analyst is positive on recent additions to senior management, he is more conservative on the market opportunity for Fabry gene therapy given the need for higher-intensity preconditioning regimens than the company has used previously, and believes that the potential adoption of value-based annuity pricing models by the industry could pose further risk to Avrobio's bottom line.
04/05/19
JANY
04/05/19
INITIATION
JANY
Buy
Avrobio initiated with a Buy at Janney Montgomery Scott
06/26/19
MZHO
06/26/19
INITIATION
Target $28
MZHO
Buy
Avrobio initiated with a Buy at Mizuho
Mizuho analyst Difei Yang initiated Avrobio with a Buy and $28 price target.

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UAL

United Continental

$94.00

2.7 (2.96%)

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FARO

Faro Technologies

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-1.27 (-2.63%)

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HWC

Hancock Whitney

$38.70

0.28 (0.73%)

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Hancock Whitney reports Q2 EPS $1.01, consensus $1.00 »

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UAL

United Continental

$94.00

2.7 (2.96%)

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  • 17

    Jul

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API crude inventories for week of July 12 »

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HOPE

Hope Bancorp

$13.96

0.2 (1.45%)

16:37
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Earnings
Hope Bancorp reports Q2 EPS 34c, consensus 34c »

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  • 17

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INO

Inovio

$3.00

0.05 (1.69%)

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IMRN

Immuron

$4.27

1.43 (50.35%)

16:32
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Syndicate
Immuron files to sell American Depositary Shares, no amount given »

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JPM

JPMorgan

$115.10

1.23 (1.08%)

, GS

Goldman Sachs

$215.57

4.02 (1.90%)

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On The Fly
Fly Intel: Wall Street's top stories for Tuesday »

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JPM

JPMorgan

$115.10

1.23 (1.08%)

GS

Goldman Sachs

$215.57

4.02 (1.90%)

JNJ

Johnson & Johnson

$132.46

-2.21 (-1.64%)

WFC

Wells Fargo

$45.30

-1.4 (-3.00%)

ARW

Arrow Electronics

$67.67

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TSLA

Tesla

$252.38

-1.03 (-0.41%)

APRN

Blue Apron

$10.33

2.68 (35.03%)

BYND

Beyond Meat

$172.50

5.9 (3.54%)

JBHT

J.B. Hunt

$97.76

5.26 (5.69%)

QTT

Qutoutiao

$4.31

-0.22 (-4.86%)

DPZ

Domino's Pizza

$246.55

-23.42 (-8.68%)

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PBYI

Puma Biotechnology

$10.78

-0.42 (-3.75%)

16:32
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FULT

Fulton Financial

$16.31

0.11 (0.68%)

16:31
07/16/19
07/16
16:31
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Earnings
Fulton Financial reports Q2 EPS 35c, consensus 34c »

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  • 17

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    Sep

WAIR

Wesco Aircraft

$10.84

0.085 (0.79%)

16:30
07/16/19
07/16
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Hot Stocks
Wesco Aircraft expans business with GKN Aerospace »

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16:30
07/16/19
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Options
Preliminary option volume of 17.5M today »

Preliminary option volume…

UBNK

United Financial

$14.07

0.05 (0.36%)

16:27
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07/16
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Earnings
United Financial reports Q2 EPS (6c), consensus 24c »

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  • 17

    Jul

ERYP

Erytech Pharma

$6.69

(0.00%)

16:24
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Syndicate
Erytech Pharma files to sell $100M of ADSs »

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CSX

CSX

$79.57

1.05 (1.34%)

16:23
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Earnings
CSX sees FY19 revenue down 1%-2% vs. prior view of growth »

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  • 16

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INAP

Internap

$3.56

0.13 (3.79%)

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FNF

Fidelity National

$41.57

0.02 (0.05%)

16:21
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Earnings
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  • 17

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RM

Regional Management

$26.62

-0.28 (-1.04%)

16:20
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Hot Stocks
Regional Management appoints Robert Beck CFO »

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  • 13

    Nov

VIX

Volatility Index S&P 500 Options

$0.00

(0.00%)

16:20
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Options
Closing CBOE SPX and VIX Index summary for July 16th »

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WLL

Whiting Petroleum

$15.54

-0.65 (-4.01%)

16:19
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Hot Stocks
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  • 13

    Aug

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UAL

United Continental

$94.00

2.7 (2.96%)

16:19
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  • 17

    Jul

CSX

CSX

$79.57

1.05 (1.34%)

16:19
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  • 16

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BPMX

BioPharmX

$0.44

-0.0183 (-3.97%)

16:19
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CCCL

China Ceramics

$0.87

(0.00%)

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