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CHMA

Chiasma

$7.37

-0.22 (-2.90%)

16:09
06/27/19
06/27
16:09
06/27/19
16:09

Chiasma provides update on Phase 3 CHIASMA OPTIMAL, MPOWERED trials

Chiasma provided an update on the clinical development of its octreotide capsules product candidate, conditionally trade-named Mycapssa, which is currently being evaluated in two ongoing, international Phase 3 clinical trials for the maintenance treatment of adults with acromegaly, the CHIASMA OPTIMAL and MPOWERED trials. In the Phase 3 CHIASMA OPTIMAL trial, which is being conducted under a special protocol assessment agreement, or SPA, with FDA, the company announced that the last enrolled patient completed the trial earlier this month. The company now expects to release top-line data by mid-Q3. All 56 patients enrolled in the trial reached the final 36-week visit with no patient dropouts from the trial reported through the 36-week double-blind and controlled phase of the trial. In the MPOWERED Phase 3 clinical trial, which is designed to support approval in the European Union, the company also announced that it has also completed enrollment. In October 2018, after 80 patients were randomized into the nine-month controlled phase of the trial, the company elected to resume enrollment in an effort to enroll additional patients exclusively located in the United States in order to gain further U.S. investigator and patient experience with octreotide capsules. Of the 146 total patients that have entered the six-month run-in phase, 84 patients have completed the run-in phase of the trial and were randomized into the nine-month randomized controlled phase, while 10 patients currently remain active in the run-in phase.

  • 10

    Jul

CHMA Chiasma
$7.37

-0.22 (-2.90%)

06/06/19
CANT
06/06/19
NO CHANGE
Target $18
CANT
Overweight
New CEO a 'significant positive' for Chiasma, says Cantor Fitzgerald
Cantor Fitzgerald analyst Brandon Folk believes the appointment of Raj Kannan as CEO is a "significant positive" for Chiasma. Kannan brings significant commercial experience to the company, and the fact that it was able to retain Mark Fitzpatrick as President is a further positive, Folk tells investors in a research note. The analyst views the news as another positive step toward a potential Mycapssa launch and the commercial readiness of Chiasma. He keeps an Overweight rating on the stock with an $18 price target.
03/07/19
CANT
03/07/19
INITIATION
Target $18
CANT
Overweight
Cantor Fitzgerald starts Chiasma with Overweight rating, $18 price target
Cantor Fitzgerald analyst Brandon Folkes earlier today initiated coverage of Chiasma with an Overweight rating and $18 price target. Since the company's Complete Response Letter from the FDA in 2016, the stock has traded at a significant discount to its potential intrinsic value, Folkes tells investors in a research note. However, he believes Chiasma's risk/reward going into Phase 3 data for Mycapssa for the treatment of acromegaly, to be released in Q3, remains positive. The analyst expects data readouts, approvals, and upward earnings revisions to drive Chiasma shares higher. Mycapssa could represent the first and only oral treatment for acromegaly when it comes to market, says Folkes. Folkes in morning trading is down 1c to $5.85.
03/07/19
03/07/19
INITIATION

Fly Intel: Top analyst initiations
Catch up on today's top analyst initiations with this list compiled by The Fly: 1. Five Below (FIVE) initiated with an Outperform at Oppenheimer. 2. Teva (TEVA) reinstated with a Buy at UBS. 3. Chiasma (CHMA) initiated with an Overweight at Cantor Fitzgerald. 4. Monster Beverage (MNST) and Constellation Brands (STZ) were initiated with an Outperform at Credit Suisse, while Procter & Gamble (PG), Coca-Cola (KO), and Church & Dwight (CHD) were initiated with a Neutral, and PepsiCo (PEP), Colgate-Palmolive (CL), and Clorox (CLX) initiated with an Underperform at Credit Suisse. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
03/07/19
CANT
03/07/19
INITIATION
Target $18
CANT
Overweight
Chiasma initiated with an Overweight at Cantor Fitzgerald
Cantor Fitzgerald initiated Chiasma with an Overweight and $18 price target.

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UTX

United Technologies

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LMT

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ARES

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-0.305 (-1.07%)

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HAFC

Hanmi Financial

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  • 23

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PAYS

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MEOH

Methanex

$43.19

0.83 (1.96%)

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  • 01

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Conference/Events
Credit Suisse biotech analysts to hold an analyst/industry conference call »

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SHIP

Seanergy Marine

$0.64

-0.0425 (-6.25%)

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SONM

Sonim

$13.42

0.24 (1.82%)

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Conference/Events
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  • 24

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KINS

Kingstone Companies

$8.81

0.09 (1.03%)

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  • 07

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Options
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BA

Boeing

$377.34

16.17 (4.48%)

, MSFT

Microsoft

$136.62

0.33 (0.24%)

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MSFT

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VIX

Volatility Index S&P 500 Options

$0.00

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$NSD

NASDAQ Market Internals

$0.00

(0.00%)

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BCBP

BCB Bancorp

$12.71

-0.09 (-0.70%)

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Earnings
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$NYE

NYSE Market Internals

$0.00

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CNXM

CNX Midstream Partners

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  • 30

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TELL

Tellurian

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General news
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ROKU

Roku

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  • 22

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