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IMUX

Immunic

$13.08

0.03 (0.23%)

06:34
08/12/19
08/12
06:34
08/12/19
06:34

Immunic enrolls first patient in IMU-838 trial for patients with PSC

Immunic announced enrollment of the first patient in an investigator-sponsored proof-of-concept clinical trial of IMU-838 for the treatment of patients with primary sclerosing cholangitis, or PSC. IMU-838 is an orally available selective immune modulator that inhibits the intracellular metabolism of activated immune cells by blocking the enzyme dihydroorotate dehydrogenase, or DHODH. PSC is a progressive disease of the liver with unknown cause and a prevalence of about 4.15 per 100,000 in the United States. Other than liver transplantation, there are currently no approved therapies that have been shown to improve survival in patients with PSC. The proof-of-concept study, for which Immunic is providing the study medication, is a single-arm, open-label, exploratory study planning to enroll a total of 30 patients with PSC, aged 18 to 75 years, who will receive 30mg IMU-838 once daily for a period of six months. The trial's primary endpoint is the change in serum alkaline phosphatase, or ALP, at six months compared to baseline. In previous trials, a biochemical endpoint such as change in serum ALP has been an accepted biomarker of disease progression in PSC patients.

IMUX Immunic
$13.08

0.03 (0.23%)

07/11/19
CHDN
07/11/19
INITIATION
Target $40
CHDN
Buy
Immunic initiated with a Buy at Chardan
Chardan analyst Taylor Feehley initiated Immunic with a Buy and $40 price target.
07/11/19
07/11/19
INITIATION

Fly Intel: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Microsoft (MSFT) initiated with an Outperform at Cowen. 2. Petrobras (PBR) initiated with a Buy at Goldman Sachs. 3. Navidea (NAVB) initiated with a Buy at Maxim. 4. Immunic (IMUX) initiated with a Buy at Chardan. 5. Target (TGT) was initiated with a Conviction Buy at Goldman Sachs, while Walmart (WMT), Home Depot (HD), Lowe's (LOW), and Costco (COST) were initiated with a Buy, and Bed Bath & Beyond (BBBY) was initiated with a Sell. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.

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TLND

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Boeing

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Nuance

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AAC Holdings

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HPQ

HP Inc.

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TRPX

Therapix Biosciences

$2.35

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GLD

SPDR Gold Shares

$141.38

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