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EW

Edwards Lifesciences

$217.35

-4.12 (-1.86%)

17:05
09/29/19
09/29
17:05
09/29/19
17:05

Edwards Lifesciences announces new data from PARTNER 3 trial

Edwards Lifesciences announced new data demonstrating early and sustained health status advantages for severe aortic stenosis patients at low surgical risk treated with the Edwards SAPIEN 3 valve. The new 1-year data, involving approximately 1,000 patients enrolled in the PARTNER 3 trial, showed significant improvements in health status as well as overall physical and mental well-being after treatment with either transcatheter aortic valve replacement with the Edwards SAPIEN 3 valve or surgical aortic valve replacement. When the treatment strategies were compared, TAVR patients improved more rapidly than surgery patients as demonstrated by a difference of 16.0 points between the groups in Kansas City Cardiomyopathy Questionnaire Overall Summary Scores at 1 month. While similar findings of early health status benefit with TAVR have been seen in prior studies of higher risk AS patients, this study also observed a sustained health status benefit of TAVR compared with SAVR at later time points of 6 months and 1 year. Furthermore, when mortality and the extent of quality of life improvement were evaluated together, the benefit of transfemoral TAVR with the SAPIEN 3 valve compared with surgery persisted through 1 year. The U.S. Food and Drug Administration approved the Edwards SAPIEN 3 and SAPIEN 3 Ultra valves for low-risk patients last month, based on data from the landmark PARTNER 3 Trial, and the launch is underway. In the PARTNER 3 Trial, TAVR with the SAPIEN 3 system achieved superiority, with a 46% reduction in the event rate for the primary endpoint of the trial, which was a composite of all-cause mortality, all stroke and rehospitalization at one year.

EW Edwards Lifesciences
$217.35

-4.12 (-1.86%)

07/24/19
FBCO
07/24/19
NO CHANGE
Target $226
FBCO
Outperform
Edwards Lifesciences price target raised to $226 from $221 at Credit Suisse
Credit Suisse analyst Matt Miksic raised his price target for Edwards Lifesciences to $226 from $221 following a "very strong" TAVR beat that bolsters case for its long-term growth potential. The analyst reiterates an Outperform rating on the shares.
07/24/19
WELS
07/24/19
NO CHANGE
Target $220
WELS
Outperform
Edwards Lifesciences price target raised to $220 from $207 at Wells Fargo
Wells Fargo analyst Lawrence Biegelsen raised his price target for Edwards Lifesciences to $220 from $207 following quarterly results. The analyst reiterates an Outperform rating on the shares.
07/24/19
RAJA
07/24/19
NO CHANGE
Target $232
RAJA
Outperform
Edwards Lifesciences price target raised to $232 from $200 at Raymond James
Raymond James analyst Jayson Bedford raised his price target for Edwards Lifesciences to $232 from $200 on increased confidence given a sharp acceleration in TAVR growth and an earlier than expected approval for Low Risk. The analyst reiterates an Outperform rating on the shares.
09/23/19
PIPR
09/23/19
INITIATION
Target $240
PIPR
Overweight
Edwards Lifesciences initiated with an Overweight at Piper Jaffray
Piper Jaffray analyst Adam Maeder started Edwards Lifesciences with an Overweight rating and $240 price target. While the company trades at "multiple turns" above its large-cap peers, the stock can continue to work at current levels, Maeder tells investors in a research note. The analyst believes there is still upside to the "already high" Street expectations in the second half of 2019 and 2020. U.S. low-risk approval should give the broader transcatheter aortic valve replacement market "a shot in the arm," says Maeder.

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