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SMMT

Summit Therapeutics

$1.70

-0.05 (-2.86%)

07:14
10/11/19
10/11
07:14
10/11/19
07:14

Summit Therapeutics expects data for Phase 3 ridinilazole program in 2H21

The company said, "Ri-CoDIFy Phase 3 landmark clinical trials aim to support adoption of the precision antibiotic ridinilazole as the new standard of care treatment for CDI by: showing superiority over the current standard of care, vancomycin, using a composite endpoint measuring sustained clinical response; generating health economic data to help support ridinilazole's commercial launch, if approved; and undertaking deep microbiome analysis that aims to show ridinilazole's preservation of the gut microbiome. The Phase 3 clinical programme remains on track for expected reporting of top-line data in the second half of 2021. The trial initiation phase is progressing well with 17 countries open for enrolment more than half of the 300 planned clinical trial sites opened, and patient enrolment at 73 and accelerating at the end of September 2019. Reported new Phase 2 clinical trial data that showed ridinilazole improved patients' quality of life compared to vancomycin, including demonstrating statistically significant early and longer-term improvements in measurements of physical and mental health. Additional data highlighted mechanistic insights into how ridinilazole preserves the healthy function of the gut microbiome in patients with CDI. These new results were reported at the ID Week Conference held in Washington DC in early October 2019. BARDA increased the total value of its award supporting the clinical and regulatory development of ridinilazole to up to $63.7M in June 2019. Under this award, BARDA exercised a $9.6M option related to patient enrolment and dosing in the Phase 3 clinical trials, bringing the total committed funding to $53.6M."

  • 11

    Oct

TODAY'S FREE FLY STORIES

NOW

ServiceNow

$254.72

-19.88 (-7.24%)

, ADBE

Adobe

$270.00

-9.4 (-3.36%)

11:28
10/16/19
10/16
11:28
10/16/19
11:28
On The Fly
Adobe downgrade, Pure Storage upgrade among today's top analyst calls »

Check out today's top…

NOW

ServiceNow

$254.72

-19.88 (-7.24%)

ADBE

Adobe

$270.00

-9.4 (-3.36%)

PSTG

Pure Storage

$18.20

0.55 (3.12%)

COST

Costco

$297.73

-0.69 (-0.23%)

WDAY

Workday

$160.48

-20.36 (-11.26%)

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WDAY

Workday

$160.53

-20.31 (-11.23%)

, COUP

Coupa Software

$145.36

-9.41 (-6.08%)

11:26
10/16/19
10/16
11:26
10/16/19
11:26
On The Fly
Workday slides as Street digests analyst day »

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WDAY

Workday

$160.53

-20.31 (-11.23%)

COUP

Coupa Software

$145.36

-9.41 (-6.08%)

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IP

International Paper

$42.22

0.79 (1.91%)

11:25
10/16/19
10/16
11:25
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11:25
Options
International Paper call volume above normal and directionally bullish »

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11:25
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11:25
Conference/Events
FBN Securities cannabis analysts to hold a luncheon meeting »

Analysts host Chairman…

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10/16/19
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11:25
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11:25
Conference/Events
William Blair restaurant tech analyst to hold a group luncheon »

Restaurant Technology…

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10/16/19
10/16
11:25
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11:25
Conference/Events
Wedbush enterprise software analysts to hold an advisor luncheon »

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TCEHY

Tencent

$0.00

(0.00%)

11:18
10/16/19
10/16
11:18
10/16/19
11:18
Periodicals
'League of Legends' coming to consoles, mobile devices, Kotaku says »

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$NSD

NASDAQ Market Internals

$0.00

(0.00%)

11:17
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10/16
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11:17
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NASDAQ market internals summary »

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$NYE

NYSE Market Internals

$0.00

(0.00%)

11:16
10/16/19
10/16
11:16
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11:16
Technical Analysis
NYSE market internals summary »

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IRBT

iRobot

$58.99

1.2 (2.08%)

11:15
10/16/19
10/16
11:15
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11:15
Options
iRobot put volume heavy and directionally bearish »

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CSCO

Cisco

$46.53

0.16 (0.35%)

11:05
10/16/19
10/16
11:05
10/16/19
11:05
Options
Cisco call volume above normal and directionally bullish »

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  • 13

    Nov

TMUS

T-Mobile

$79.88

0.13 (0.16%)

, S

Sprint

$6.46

-0.02 (-0.31%)

10:51
10/16/19
10/16
10:51
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10:51
Hot Stocks
FCC commissioner Rosenworcel says T-Mobile, Sprint deal will raise prices »

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TMUS

T-Mobile

$79.88

0.13 (0.16%)

S

Sprint

$6.46

-0.02 (-0.31%)

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  • 22

    Oct

SIG

Signet Jewelers

$15.36

-0.39 (-2.48%)

10:50
10/16/19
10/16
10:50
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10:50
Options
Call volume in Signet Jewelers spikes on large 3-way adjusting long »

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UAL

United Airlines

$89.13

1.23 (1.40%)

10:50
10/16/19
10/16
10:50
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10:50
Hot Stocks
United Airlines sees potential for higher fares over holidays »

Management says all hubs…

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INCY

Incyte

$78.05

-0.47 (-0.60%)

10:47
10/16/19
10/16
10:47
10/16/19
10:47
Recommendations
Incyte analyst commentary  »

Incyte REACH2 'a…

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PNC

PNC Financial

$143.07

3.51 (2.52%)

10:47
10/16/19
10/16
10:47
10/16/19
10:47
Hot Stocks
Breaking Hot Stocks news story on PNC Financial »

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PNC

PNC Financial

$143.11

3.55 (2.54%)

10:45
10/16/19
10/16
10:45
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10:45
Hot Stocks
Breaking Hot Stocks news story on PNC Financial »

PNC Financial sees one…

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PNC

PNC Financial

$143.11

3.55 (2.54%)

10:45
10/16/19
10/16
10:45
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10:45
Hot Stocks
Breaking Hot Stocks news story on PNC Financial »

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UAL

United Airlines

$89.05

1.15 (1.31%)

, BA

Boeing

$370.43

-0.56 (-0.15%)

10:43
10/16/19
10/16
10:43
10/16/19
10:43
Hot Stocks
Breaking Hot Stocks news story on United Airlines, Boeing »

United Airlines says…

UAL

United Airlines

$89.05

1.15 (1.31%)

BA

Boeing

$370.43

-0.56 (-0.15%)

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PNC

PNC Financial

$143.12

3.56 (2.55%)

10:43
10/16/19
10/16
10:43
10/16/19
10:43
Hot Stocks
Breaking Hot Stocks news story on PNC Financial »

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UAL

United Airlines

$88.99

1.09 (1.24%)

10:42
10/16/19
10/16
10:42
10/16/19
10:42
Hot Stocks
United Airlines plans to increase aircraft size to help with costs »

Comments provided during…

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CBRE

CBRE Group

$52.66

0.19 (0.36%)

10:40
10/16/19
10/16
10:40
10/16/19
10:40
Options
Size put roll is legged in CBRE Group »

Size put roll is legged…

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  • 06

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10:35
10/16/19
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10:35
General news
FX Action: USD-CAD »

FX Action: USD-CAD popped…

PNC

PNC Financial

$142.83

3.27 (2.34%)

10:34
10/16/19
10/16
10:34
10/16/19
10:34
Hot Stocks
PNC Financial notes 'obvious unanswered questions' about operating environment »

Comments taken from Q3…

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  • 16

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ALXN

Alexion

$102.75

-2.095 (-2.00%)

, ACHN

Achillion

$6.34

2.685 (73.46%)

10:31
10/16/19
10/16
10:31
10/16/19
10:31
Recommendations
Alexion, Achillion analyst commentary  »

Piper likes Alexion…

ALXN

Alexion

$102.75

-2.095 (-2.00%)

ACHN

Achillion

$6.34

2.685 (73.46%)

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