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AZRX

AzurRx BioPharma

$0.45

-0.0352 (-7.31%)

07:40
10/15/19
10/15
07:40
10/15/19
07:40

AzurRx BioPharma announces first patients dosed in MS1819-SD clinical trial

AzurRx BioPharma announced that it has dosed the first patients in its Phase 2 clinical trial to investigate MS1819-SD in combination with standard porcine enzyme replacement therapy for patients with cystic fibrosis who suffer from severe exocrine pancreatic insufficiency. This subset of CF patients experiences clinical symptoms of fat malabsorption, despite taking the maximum daily dose of PERTs. The Phase 2 multi-center study is designed to investigate the safety, tolerability and efficacy of escalating doses of MS1819-SD, which is a yeast-derived lipase, in conjunction with a stable dose of porcine PERTs, in order to increase the coefficient of fat absorption and relieve abdominal symptoms. A combination therapy of PERT and MS1819-SD has the potential to: correct macronutrient and micronutrient maldigestion; eliminate abdominal symptoms attributable to maldigestion; and sustain optimal nutritional status on a normal diet in CF patients with severe EPI. Planned enrollment is expected to include approximately 24 CF patients with severe EPI, with study completion anticipated in 2020.

AZRX AzurRx BioPharma
$0.45

-0.0352 (-7.31%)

01/25/19
ROTH
01/25/19
INITIATION
Target $10.5
ROTH
Buy
AzurRx BioPharma initiated with a Buy at Roth Capital
Roth Capital analyst Jerry Isaacson initiated AzurRx BioPharma with a Buy rating and $10.50 price target. In a research note to investors, Isaacson says he assumes MS1819 to treat EPI in CF patients will be approved for the patient population in 2022, and says his model includes pricing starting at $18,000 per patient per year, in line with currently approved PERTs. MS1819 has numerous potential advantages over currently approved treatments, including reduced pill burden, and the fact that it is not derived from an animal source, he adds.
01/25/19
01/25/19
INITIATION

Fly Intel: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. SS&C (SSNC) initiated with a Buy at Buckingham. 2. Capital Southwest (CSWC) initiated with a Neutral at B. Riley FBR. 3. Natural Gas Services (NGS) initiated with a Buy at Maxim. 4. Aptose Biosciences (APTO) initiated with an Outperform at Oppenheimer. 5. AzurRx BioPharma (AZRX) initiated with a Buy at Roth Capital. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
02/14/19
MAXM
02/14/19
INITIATION
Target $5
MAXM
Buy
AzurRx BioPharma initiated with a Buy at Maxim
Maxim analyst Caroline Palomeque initiated AzurRx BioPharma with a Buy rating and a price target of $5. The analyst cites the company's prioritizing of MS1819-SD development in Cystic Fibrosis given the "relatively undifferentiated" Pancreatic Enzyme Replacement Therapy market, stating the drug would be the "first non-porcine product available for exocrine pancreatic insufficiency that lowers pill burden, reduces risk of allergic reaction and improves quality of life".
06/11/19
NATL
06/11/19
INITIATION
Target $9
NATL
Buy
AzurRx BioPharma initiated with a Buy at National Securities
National Securities analyst Jonathan Aschoff initiated AzurRx BioPharma with a Buy rating and $9 price target.

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Hertz

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MSFT

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UAL

United Airlines

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FAST

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