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OPGN

OpGen

$1.11

0.04 (3.76%)

07:41
11/19/19
11/19
07:41
11/19/19
07:41

OpGen says products in development to address 'urgent threat' pathogens

OpGen announced that the Center for Disease Control has released updated data increasing the number of deaths in the United States from antibiotic-resistant bacteria and fungi, and highlighting the continuing threat of rising antibiotic resistance. According to the CDC, these pathogens cause more than 2.8 million infections and 35,000 deaths in the U.S. each year. That means, on average, someone in the United States gets an antibiotic-resistant infection every 11 seconds, and every 15 minutes, someone dies. OpGen's products have been developed to help combat these growing threats. The Acuitas AMR Gene Panel test, currently in development, is designed to help identify drug-resistant pathogens directly from urine as an aid in the diagnosis of urinary tract infections in under three hours. The Acuitas Lighthouse Software, also in development, is currently being tested in a state-wide initiative to help quickly identify and track urgent threat pathogens. The Acuitas AMR Gene Panel test is being developed for patients at risk for complicated urinary tract infections and is designed to test for up to five pathogens and up to 47 antimicrobial genes. When paired with the Acuitas Lighthouse Software, OpGen believes the test will be able to help improve management of the more than one million patients in the United States with cUTI. Specifically, the Acuitas AMR Gene Panel test, in combination with the Acuitas Lighthouse Software, both in development, can help test for and identify major concerns for hospital patients, including Carbapenem-Resistant Enterobacteriaceae, Multidrug-Resistant Pseudomonas Aeruginosa, and Extended-Spectrum Beta-Lactamase Producing Enterobacteriaceae. OpGen is conducting clinical trials in 2019 to support a submission for the direct-from-urine Acuitas AMR Gene Panel test and for the Acuitas Lighthouse Software for antibiotic resistance prediction for the management of antimicrobial resistance data in healthcare institutions. Earlier this year, clinical trials were conducted for establishing the performance of the Acuitas AMR Gene Panel for use with bacterial isolates. Data obtained from the clinical trials were submitted in a 510(k) submission which is currently under review by the U.S. Food and Drug Administration.

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