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TNXP

Tonix Pharmaceuticals

$1.39 /

-0.11 (-7.33%)

16:18
01/29/20
01/29
16:18
01/29/20
16:18

Tonix Pharmaceuticals presents TNX-801 results at ASM Biothreats Conference

Tonix Pharmaceuticals presented preclinical results of TNX-801 to potentially prevent smallpox and monkeypox in a poster at the 2020 ASM Biothreats Conference. The poster includes preclinical safety and efficacy analyses of TNX-801. The poster can be found on the Scientific Presentations page of Tonix's website. Cynomolgus macaques were vaccinated with either high dose or low dose TNX-801, TNX-1200, or vehicle control. The poster presentation reports that all animals vaccinated with TNX-801 were fully protected with sterilizing immunity from a challenge with intra-tracheal monkeypox. In contrast, two of three evaluable animals vaccinated with TNX-1200, and all animals who received the vehicle control, developed monkeypox lesions after challenge. In addition, after a single vaccination, four of four animals vaccinated with high dose of TNX-801 and three of four animals vaccinated with a low dose of TNX-801 responded with a cutaneous reaction called a "take" that is a biomarker of protective immunity in immunocompetent individuals in campaigns to control smallpox contagion. In contrast, only one of three animals vaccinated with a low dose of TNX-1200 responded with a take. The vaccinations with TNX-801 or TNX-1200 were well tolerated. TNX-801 and TNX-1200 are in the preclinical and pre-Investigational New Drug (IND) application stage of development. Tonix is developing TNX-801 and TNX-1200 as potential smallpox preventing vaccines for the U.S. strategic national stockpile and as monkeypox preventing vaccines for areas where monkeypox is a growing problem.

  • 26

    Mar

TNXP Tonix Pharmaceuticals
$1.39 /

-0.11 (-7.33%)

08/30/19 Roth Capital
Tonix Pharmaceuticals price target lowered to $1.30 from $4 at Roth Capital
04/18/19
Tonix Pharmaceuticals upgraded to Buy at Roth Capital
04/18/19 Roth Capital
Tonix Pharmaceuticals upgraded to Buy from Neutral at Roth Capital

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