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ONTX

Onconova

$0.36 /

+0.052 (+16.67%)

16:14
03/24/20
03/24
16:14
03/24/20
16:14

Onconova announces completion of patient enrollment in INSPIRE trial

"Following significant progress throughout 2019, our team's immediate focus remains to advance our pivotal Phase 3 INSPIRE trial to the next milestone," said Steven Fruchtman, president and CEO. "We are excited to announce the completion of the planned enrollment of 360 patients in the INSPIRE trial in higher-risk (HR) MDS patients. INSPIRE represents one of the largest studies ever conducted in this patient population. Based on survival trends on the INSPIRE trial to date, we anticipate reporting topline survival data in the second half of 2020 and presenting the results at a medical meeting later this year. We continue to analyze deep genomic sequencing, including mutations of the Ras pathway, on these patients. Important genomic results were presented at ASH 2019 and additional data is expected to be presented at future medical meetings." Fruchtman continued, "We are also pleased about the progress of our plans for additional investigator-initiated studies - including the Phase 1/2a study of rigosertib plus nivolumab for the treatment of Stage IV KRAS mutated lung adenocarcinoma. We anticipate the first patient to be entered onto the trial once the COVID-19 environment improves sufficiently."

  • 24

    Mar

ONTX Onconova
$0.36 /

+0.052 (+16.67%)

11/26/19 Maxim
Onconova downgraded to Hold from Buy at Maxim
07/25/19
Fly Intel: Top five analyst initiations
07/25/19 Noble Capital
Onconova initiated with an Outperform at Noble Capital

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