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ALRN

Aileron Therapeutics

$0.91 /

+0.0892 (+10.88%)

08:41
05/27/20
05/27
08:41
05/27/20
08:41

Aileron Therapeutics initiates expansion cohort of Phase 1b/2 study of ALRN-6924

Aileron Therapeutics announced the expansion of one of the dose levels in the dose optimization part of its Phase 1b/2 clinical trial evaluating ALRN-6924 as an agent to protect patients with small cell lung cancer against chemotherapy-induced toxicity, a concept known as chemoprotection. The first patient has been enrolled into the expansion cohort, which was triggered by results from the ongoing trial that met protocol-specified criteria for expansion. The Company expects to enroll approximately 8 patients into this dose optimization expansion cohort to further evaluate the selected dose for chemoprotection from topotecan-induced bone marrow toxicities. The Phase 1b study is designed to identify a dose and a schedule of ALRN-6924 administration to reduce chemotherapy toxicities such as severe anemia and thrombocytopenia, and other toxicities resulting from topotecan. ALRN-6924 is administered 24 hours or six hours before each dose of topotecan, which is administered daily on days 1 through 5 of every 21-day treatment cycle. Aileron currently plans to report interim results for the dose optimization part of the trial in June 2020. The Company plans to report the top-line final data for the dose optimization part of the trial, including this expansion cohort, and data for the schedule optimization part of the trial in the fourth quarter of 2020. The Company expects that these results will determine a recommended ALRN-6924 dose and schedule for subsequent trials. The Company continues to enroll patients into its chemoprotection trial while carefully monitoring the effect of the coronavirus pandemic on its clinical trial sites and the healthcare system, which may impact the timing of these planned data announcements.

  • 17

    Jun

ALRN Aileron Therapeutics
$0.91 /

+0.0892 (+10.88%)

04/08/20 JonesTrading
Aileron Therapeutics initiated with a Buy at JonesTrading
04/08/20 JonesTrading
Aileron Therapeutics initiated with a Buy at JonesTrading
03/31/20 H.C. Wainwright
Aileron Therapeutics price target lowered to $3 from $6 at H.C. Wainwright

TODAY'S FREE FLY STORIES

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+0.61 (+0.62%)

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VRNS Varonis
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+0.61 (+0.62%)

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Hot Stocks
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NanoVibronix

$2.20 /

+0.25 (+12.82%)

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NAOV NanoVibronix
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Hot Stocks
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UBER Uber
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Curis

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CRIS Curis
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Internap

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+ (+0.00%)

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Hot Stocks
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INSM

Insmed

$28.66 /

-0.93 (-3.14%)

Insmed announced that…

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INSM Insmed
$28.66 /

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INSM Insmed
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Hot Stocks
Happiness Biotech receives NPN license in Canada for hand sanitizer » 08:06
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HAPP

Happiness Biotech

$2.82 /

+0.03 (+1.08%)

Happiness Biotech…

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HAPP Happiness Biotech
$2.82 /

+0.03 (+1.08%)

HAPP Happiness Biotech
$2.82 /

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12/06/19 Aegis
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  • 25
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Initiation
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PCVX

Vaxcyte

$29.35 /

-0.7 (-2.33%)

Jefferies analyst Biren…

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PCVX Vaxcyte
$29.35 /

-0.7 (-2.33%)

06:54 Today Needham
Vaxcyte initiated with a Buy at Needham
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  • 12
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PCVX Vaxcyte
$29.35 /

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Hot Stocks
PriceSmart announces June net merchandise sales down 1.5% to $249.2M » 08:04
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PriceSmart

$60.15 /

+0.38 (+0.64%)

PriceSmart announced that…

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PSMT PriceSmart
$60.15 /

+0.38 (+0.64%)

PSMT PriceSmart
$60.15 /

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PSMT PriceSmart
$60.15 /

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Earnings
Silicon Motion sees Q2 revenue at lower half of $133M-$143M, consensus $139.07M » 08:04
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SIMO

Silicon Motion

$48.43 /

+0.17 (+0.35%)

Gross margin is expected…

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SIMO Silicon Motion
$48.43 /

+0.17 (+0.35%)

SIMO Silicon Motion
$48.43 /

+0.17 (+0.35%)

06/26/20 KeyBanc
Memory supply remains limited in 2H amid low visibility, says KeyBanc
06/22/20 Cowen
Silicon Motion price target raised to $60 from $54 at Cowen
04/30/20 Craig-Hallum
Silicon Motion price target raised to $55 from $50 at Craig-Hallum
04/29/20 Craig-Hallum
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SIMO Silicon Motion
$48.43 /

+0.17 (+0.35%)

SIMO Silicon Motion
$48.43 /

+0.17 (+0.35%)

Hot Stocks
CSG extends agreement with Bell Canada » 08:04
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08:04
CSGS

CSG

$40.77 /

-0.41 (-1.00%)

CSG and Bell,…

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CSGS CSG
$40.77 /

-0.41 (-1.00%)

CSGS CSG
$40.77 /

-0.41 (-1.00%)

03/10/20 Sidoti
CSG upgraded to Buy from Neutral at Sidoti
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CSG downgraded to Neutral from Buy at Sidoti
CSGS CSG
$40.77 /

-0.41 (-1.00%)

Hot Stocks
MYOS announces publication of study evaluating Fortetropin » 08:03
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MYOS

$1.38 /

-0.28 (-16.87%)

MYOS RENS Technology…

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MYOS MYOS
$1.38 /

-0.28 (-16.87%)

MYOS MYOS
$1.38 /

-0.28 (-16.87%)

Hot Stocks
Accenture, AT&T working with Phillips 66 on industrial cellular connectivity » 08:03
07/07/20
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08:03
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ACN

Accenture

$217.57 /

+1.71 (+0.79%)

, T

AT&T

$30.50 /

+0.42 (+1.40%)

, PSX

Phillips 66

$68.05 /

-0.29 (-0.42%)

Accenture (ACN) and…

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ACN Accenture
$217.57 /

+1.71 (+0.79%)

T AT&T
$30.50 /

+0.42 (+1.40%)

PSX Phillips 66
$68.05 /

-0.29 (-0.42%)

ACN Accenture
$217.57 /

+1.71 (+0.79%)

06/26/20 Susquehanna
Accenture price target raised to $250 from $225 at Susquehanna
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$30.50 /

+0.42 (+1.40%)

06/25/20 BTIG
RingCentral price target raised to $325 from $275 at BTIG
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Electronic Arts seems like best fit as buyer for WB Interactive, says Stephens
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EA makes 'most sense' as potential buyer of Warner gaming unit, says Oppenheimer
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PSX Phillips 66
$68.05 /

-0.29 (-0.42%)

06/23/20 Jefferies
DCP Midstream, Phillips 66 and Holly Energy Partners cut to Hold at Jefferies
06/23/20 Jefferies
Phillips 66 downgraded to Hold from Buy at Jefferies
05/21/20 US Capital Advisors
Phillips 66 downgraded to Overweight from Buy at US Capital Advisors
05/13/20 Wolfe Research
Phillips 66 downgraded to Peer Perform from Outperform at Wolfe Research
ACN Accenture
$217.57 /

+1.71 (+0.79%)

T AT&T
$30.50 /

+0.42 (+1.40%)

PSX Phillips 66
$68.05 /

-0.29 (-0.42%)

ACN Accenture
$217.57 /

+1.71 (+0.79%)

T AT&T
$30.50 /

+0.42 (+1.40%)

PSX Phillips 66
$68.05 /

-0.29 (-0.42%)

ACN Accenture
$217.57 /

+1.71 (+0.79%)

T AT&T
$30.50 /

+0.42 (+1.40%)

ACN Accenture
$217.57 /

+1.71 (+0.79%)

T AT&T
$30.50 /

+0.42 (+1.40%)

PSX Phillips 66
$68.05 /

-0.29 (-0.42%)

Initiation
Corbus Pharmaceuticals initiated with a Buy at Roth Capital » 08:02
07/07/20
07/07
08:02
07/07/20
08:02
CRBP

Corbus Pharmaceuticals

$7.90 /

-0.05 (-0.63%)

Roth Capital analyst…

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CRBP Corbus Pharmaceuticals
$7.90 /

-0.05 (-0.63%)

CRBP Corbus Pharmaceuticals
$7.90 /

-0.05 (-0.63%)

06/22/20 BTIG
Corbus Pharmaceuticals' Phase 2b CF data readouts seen in Q3, says BTIG
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Corbus Pharmaceuticals initiated with a Buy at BTIG
06/03/20 Nomura Instinet
Corbus Pharmaceuticals price target raised to $32 from $12 at Nomura Instinet
03/26/20
Fly Intel: Top five analyst initiations
CRBP Corbus Pharmaceuticals
$7.90 /

-0.05 (-0.63%)

  • 07
    Feb
Options
Alibaba call buyer realizes 16% same-day gains » 08:00
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08:00
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BABA

Alibaba

$239.98 /

+16.56 (+7.41%)

Notable profits for the…

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BABA Alibaba
$239.98 /

+16.56 (+7.41%)

BABA Alibaba
$239.98 /

+16.56 (+7.41%)

06/19/20 Barclays
Alibaba price target raised to $270 from $260 at Barclays
06/19/20 Morgan Stanley
6.18 promotion in China released pent-up buying demand, says Morgan Stanley
06/08/20 Bernstein
Pinduoduo initiated with an Outperform at Bernstein
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Alibaba price target raised to $275 from $260 at Susquehanna
BABA Alibaba
$239.98 /

+16.56 (+7.41%)

BABA Alibaba
$239.98 /

+16.56 (+7.41%)

BABA Alibaba
$239.98 /

+16.56 (+7.41%)

BABA Alibaba
$239.98 /

+16.56 (+7.41%)

Hot Stocks
Vaccinex remains on track to complete SIGNAL trial in HD on time » 07:59
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07/07
07:59
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07:59
VCNX

Vaccinex

$3.70 /

+0.325 (+9.63%)

Vaccinex announced that,…

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VCNX Vaccinex
$3.70 /

+0.325 (+9.63%)

VCNX Vaccinex
$3.70 /

+0.325 (+9.63%)

VCNX Vaccinex
$3.70 /

+0.325 (+9.63%)

Hot Stocks
Rollins jumps 7% to $45.85 after providing Q2 revenue guidance  07:59
07/07/20
07/07
07:59
07/07/20
07:59
ROL

Rollins

$42.73 /

-0.29 (-0.67%)

 
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ROL Rollins
$42.73 /

-0.29 (-0.67%)

ROL Rollins
$42.73 /

-0.29 (-0.67%)

06/05/20 Stifel
Rollins takeout seems unlikely given current valuation, says Stifel
11/21/19 Jefferies
Jefferies initiates Diversifed Services sector
11/21/19 Jefferies
Rollins initiated with a Hold at Jefferies
11/06/19
Fly Intel: Top five analyst upgrades
ROL Rollins
$42.73 /

-0.29 (-0.67%)

ROL Rollins
$42.73 /

-0.29 (-0.67%)

Recommendations
Skechers price target raised to $34 from $28 at Wedbush » 07:58
07/07/20
07/07
07:58
07/07/20
07:58
SKX

Skechers

$29.69 /

-0.54 (-1.79%)

Wedbush analyst…

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SKX Skechers
$29.69 /

-0.54 (-1.79%)

SKX Skechers
$29.69 /

-0.54 (-1.79%)

07/01/20 OTR Global
Skechers initiated with a Mixed at OTR Global
06/17/20 UBS
Skechers traction with consumers improving, says UBS
05/14/20 Wells Fargo
Wells Fargo downgrades Steven Madden to Underweight on brand weakness
04/24/20 Susquehanna
Skechers brand strength helps mitigate crisis, says Susquehanna
SKX Skechers
$29.69 /

-0.54 (-1.79%)

SKX Skechers
$29.69 /

-0.54 (-1.79%)

SKX Skechers
$29.69 /

-0.54 (-1.79%)

Downgrade
Northland downgrades Healthcare Services on headline, legal risk from COVID-19 » 07:56
07/07/20
07/07
07:56
07/07/20
07:56
HCSG

Healthcare Services

$24.24 /

-0.05 (-0.21%)

As previously reported,…

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HCSG Healthcare Services
$24.24 /

-0.05 (-0.21%)

HCSG Healthcare Services
$24.24 /

-0.05 (-0.21%)

07:39 Today Northland
Healthcare Services downgraded to Market Perform from Outperform at Northland
07/06/20 Benchmark
Healthcare Services downgraded to Hold from Buy at Benchmark
04/22/20 Credit Suisse
Healthcare Services price target lowered to $27 from $32 at Credit Suisse
04/20/20 Baird
Healthcare Services upgraded to Outperform from Neutral at Baird
HCSG Healthcare Services
$24.24 /

-0.05 (-0.21%)

HCSG Healthcare Services
$24.24 /

-0.05 (-0.21%)

Initiation
Organigram initiated with a Buy at Alliance Global Partners » 07:56
07/07/20
07/07
07:56
07/07/20
07:56
OGI

Organigram

$1.56 /

-0.065 (-4.01%)

Alliance Global Partners…

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OGI Organigram
$1.56 /

-0.065 (-4.01%)

OGI Organigram
$1.56 /

-0.065 (-4.01%)

06/29/20 Raymond James
Organigram downgraded to Market Perform from Outperform at Raymond James
06/29/20 Raymond James
Organigram downgraded to Market Perform from Outperform at Raymond James
04/15/20 CIBC
Organigram downgraded to Neutral from Outperformer at CIBC
04/01/20 Cantor Fitzgerald
Organigram price target lowered to C$5.80 from C$9.00 at Cantor Fitzgerald
OGI Organigram
$1.56 /

-0.065 (-4.01%)

OGI Organigram
$1.56 /

-0.065 (-4.01%)

OGI Organigram
$1.56 /

-0.065 (-4.01%)

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