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GBT

Global Blood Therapeutics

$67.46 /

+0.88 (+1.32%)

08:36
06/24/20
06/24
08:36
06/24/20
08:36

Global Blood Therapeutics to seek regulatory approval for Oxbryta

Global Blood Therapeutics announced that it plans to submit a Marketing Authorization Application to the European Medicines Agency for Oxbryta tablets to treat hemolytic anemia in sickle cell disease patients ages 12 years and older. The company plans to submit the MAA by mid-2021. An oral, once daily therapy, Oxbryta directly inhibits hemoglobin polymerization, the root cause of the sickling and destruction of red blood cells in SCD. The sickling process causes hemolytic anemia, which impairs adequate oxygen delivery to the tissues and organs in the body. Based on recent discussions with the EMA, GBT intends to seek full marketing authorization of Oxbryta. The planned MAA will include data from the Phase 3 HOPE Study and the Phase 2 HOPE-KIDS 1 Study, both of which enrolled patients at clinical sites in Europe. GBT also intends to initiate an Early Access Program in Europe for patients and physicians who may need access to Oxbryta prior to potential marketing authorization. In Europe, an estimated 52,000 people are living with SCD. In recognition of the need for new SCD treatments, the EMA granted Oxbryta Priority Medicines designation, and the European Commission designated Oxbryta as an orphan medicinal product for the treatment of patients with SCD. Oxbryta received U.S. Food and Drug Administration accelerated approval for the treatment of SCD in adults and children 12 years of age and older on November 25, 2019. Earlier this month, GBT announced plans to expand the potential use of Oxbryta in the United States for the treatment of SCD in children ages 4 to 11 years.

GBT Global Blood Therapeutics
$67.46 /

+0.88 (+1.32%)

06/12/20 Wells Fargo
Global Blood's Oxbryta efficacy bar 'tough to surpass,' says Wells Fargo
06/09/20 Cantor Fitzgerald
Global Blood filing pathway increases opportunity, says Cantor Fitzgerald
05/27/20 Piper Sandler
Global Blood launch of Oxbryta tracking favorably, says Piper Sandler
05/07/20 Wells Fargo
Global Blood Therapeutics price target raised to $133 from $122 at Wells Fargo

TODAY'S FREE FLY STORIES

Recommendations
Peloton promotion with Chase a positive subscriber catalyst, says KeyBanc » 10:50
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10:50
10/27/20
10:50
PTON

Peloton

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JPMorgan

$100.00 /

-1.205 (-1.19%)

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PTON Peloton
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JPM JPMorgan
$100.00 /

-1.205 (-1.19%)

PTON Peloton
/

+

10/21/20 Goldman Sachs
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+

JPM JPMorgan
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-1.205 (-1.19%)

PTON Peloton
/

+

JPM JPMorgan
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PTON Peloton
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+

JPM JPMorgan
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PTON Peloton
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Recommendations
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STZHF

Stelco Holdings

$0.00 /

+ (+0.00%)

Scotiabank analyst…

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STZHF Stelco Holdings
$0.00 /

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10/15/20 National Bank
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General news
FX Action: USD-JPY » 10:50
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FX Action: USD-JPY…

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Treasury Action: bonds are rallying as Wall Street is losing its foothold » 10:50
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Hot Stocks
Republic First Bancorp postpones release of Q3 results » 10:50
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10/27
10:50
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FRBK

Republic First Bancorp

$2.31 /

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Republic First Bancorp…

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SLF

Sun Life Financial

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-0.49 (-1.19%)

Scotiabank analyst Meny…

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SLF Sun Life Financial
$40.65 /

-0.49 (-1.19%)

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Hot Stocks
Daimler, Waymo partner on self-driving Freightliner trucks » 10:48
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DDAIF

Daimler AG

$0.00 /

+ (+0.00%)

Daimler Trucks and Waymo…

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DDAIF Daimler AG
$0.00 /

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DDAIF Daimler AG
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Recommendations
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Scholar Rock

$23.55 /

+9.81 (+71.40%)

Baird analyst Madhu Kumar…

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SRRK Scholar Rock
$23.55 /

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Recommendations
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GWLIF

Great-West Lifeco

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Scotiabank analyst Meny …

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GWLIF Great-West Lifeco
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10/05/20 National Bank
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Hot Stocks
JPMorgan Chase announces Sapphire cardmember partnership with Peloton » 10:46
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PTON

Peloton

$119.96 /

+1.83 (+1.55%)

, JPM

JPMorgan

$99.97 /

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Earlier today, Chase, the…

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PTON Peloton
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+1.83 (+1.55%)

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PTON Peloton
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Earnings
Polaris sees Q4 revenue growing sequentially, consensus $1.95B » 10:46
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PII

Polaris

$91.51 /

-0.16 (-0.17%)

Sees margins "coming…

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PII Polaris
$91.51 /

-0.16 (-0.17%)

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$91.51 /

-0.16 (-0.17%)

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Hot Stocks
Green Brick shares remain 'deeply undervalued,' Greenlight's Einhorn says » 10:45
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GRBK

Green Brick

$17.62 /

-0.08 (-0.45%)

David Einhorn of…

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GRBK Green Brick
$17.62 /

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General news
The Richmond Fed surge » 10:45
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The Richmond Fed surge to…

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Options
Pacific Ethanol call volume above normal and directionally bullish » 10:45
10/27/20
10/27
10:45
10/27/20
10:45
PEIX

Pacific Ethanol

$7.15 /

-0.77 (-9.72%)

Bullish option flow…

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PEIX Pacific Ethanol
$7.15 /

-0.77 (-9.72%)

PEIX Pacific Ethanol
$7.15 /

-0.77 (-9.72%)

09/29/20 Craig-Hallum
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-0.77 (-9.72%)

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General news
8-Week Bill Announcement to be released at 11:00  10:45
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General news
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Recommendations
Intact Financial price target raised to C$161 from C$155 at Scotiabank » 10:44
10/27/20
10/27
10:44
10/27/20
10:44
IFCZF

Intact Financial

$0.00 /

+ (+0.00%)

Scotiabank analyst Phil…

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IFCZF Intact Financial
$0.00 /

+ (+0.00%)

10/21/20 National Bank
Intact Financial price target raised to C$168 from C$165 at National Bank
10/21/20 TD Securities
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07/31/20 CIBC
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07/30/20 CIBC
Intact Financial price target raised to C$155 from C$140 at CIBC
Recommendations
Fairfax Financial price target lowered to C$500 from C$600 at Scotiabank » 10:44
10/27/20
10/27
10:44
10/27/20
10:44
FRFHF

Fairfax Financial

$0.00 /

+ (+0.00%)

Scotiabank analyst Phil…

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FRFHF Fairfax Financial
$0.00 /

+ (+0.00%)

FRFHF Fairfax Financial
$0.00 /

+ (+0.00%)

07/23/20 Scotiabank
Fairfax Financial price target raised to C$600 from C$580 at Scotiabank
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Recommendations
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10/27
10:42
10/27/20
10:42
CDNAF

Canadian Tire

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CDNAF Canadian Tire
$0.00 /

+ (+0.00%)

10/23/20 CIBC
Canadian Tire price target raised to C$162 from C$141 at CIBC
10/19/20 National Bank
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Recommendations
Cascades price target raised to C$17.50 from C$16.50 at TD Securities » 10:41
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10/27
10:41
10/27/20
10:41
CADNF

Cascades

$0.00 /

+ (+0.00%)

TD Securities analyst…

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CADNF Cascades
$0.00 /

+ (+0.00%)

CADNF Cascades
$0.00 /

+ (+0.00%)

10/26/20 CIBC
Cascades price target raised to C$22 from C$21 at CIBC
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Recommendations
Trisura Group price target raised to C$105 from C$100 at TD Securities » 10:40
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10/27
10:40
10/27/20
10:40
TRRSF

Trisura Group

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TRRSF Trisura Group
$0.00 /

+ (+0.00%)

10/14/20 CIBC
Trisura Group initiated with an Outperformer at CIBC
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Recommendations
Chorus Aviation price target lowered to C$5.50 from C$6.50 at TD Securities » 10:40
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10/27
10:40
10/27/20
10:40
CHRRF

Chorus Aviation

$0.00 /

+ (+0.00%)

TD Securities analyst Tim…

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CHRRF Chorus Aviation
$0.00 /

+ (+0.00%)

10/26/20 CIBC
Chorus Aviation price target raised to C$5 from C$4.25 at CIBC
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General news
The modest October drop in U.S. consumer confidence » 10:40
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10:40
10/27/20
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The modest October drop…

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Recommendations
AirBoss of America price target raised to C$31 from C$29 at TD Securities » 10:39
10/27/20
10/27
10:39
10/27/20
10:39
ABSSF

AirBoss of America

$0.00 /

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TD Securities analyst Tim…

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ABSSF AirBoss of America
$0.00 /

+ (+0.00%)

ABSSF AirBoss of America
$0.00 /

+ (+0.00%)

08/12/20 CIBC
AirBoss of America price target raised to C$35 from C$33 at CIBC
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AirBoss of America price target raised to C$31 from C$27 at Canaccord
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AirBoss of America price target raised to C$33 from C$23 at CIBC
Hot Stocks
JetBlue doesn't see Covid vaccine as a panacea  10:35
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10:35
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10:35
JBLU

JetBlue

$12.19 /

-0.38 (-3.02%)

 
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$12.19 /

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JBLU JetBlue
$12.19 /

-0.38 (-3.02%)

JBLU JetBlue
$12.19 /

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JBLU JetBlue
$12.19 /

-0.38 (-3.02%)

JBLU JetBlue
$12.19 /

-0.38 (-3.02%)

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