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RVMD

Revolution Medicines

$34.98 /

+1.16 (+3.43%)

, AMGN

Amgen

$234.68 /

-2.06 (-0.87%)

07:19
04/30/21
04/30
07:19
04/30/21
07:19

Revolution Medicines does not expect RMC-4630, sotorasib data in 2021

Revolution Medicines (RVMD) said that after consultation with Amgen (AMGN), it is providing an update to investors regarding the Amgen-sponsored Phase 1b study of RMC-4630 in combination with Amgen's KRASG12C inhibitor, AMG 510 or sotorasib, as part of Amgen's CodeBreak 101 study. To date, the available data from the RMC-4630 and sotorasib combination in this ongoing study has "demonstrated acceptable tolerability and cleared early dose levels," the company said in a regulatory filing. Amgen's CodeBreaK 101c study is currently dosing patients at the RMC-4630 target dose of 200 mg on a Day 1/Day 2 weekly schedule. Revolution said it "looks forward to selection of a combination dose in the second half of 2021." The company does not currently expect clinical data from the RMC-4630 and sotorasib combination to be provided in 2021. Revolution expects Amgen, as sponsor of this study, to report data from CodeBreaK 101c at a future date to be determined at Amgen's discretion.

RVMD

Revolution Medicines

$34.98 /

+1.16 (+3.43%)

AMGN

Amgen

$234.68 /

-2.06 (-0.87%)

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RVMD Revolution Medicines
$34.98 /

+1.16 (+3.43%)

03/03/21 SVB Leerink
Revolution Medicines price target raised to $55 from $46 at SVB Leerink
01/29/21 JPMorgan
Revolution Medicines price target raised to $44 from $33 at JPMorgan
10/26/20 H.C. Wainwright
Revolution Medicines price target raised to $54 from $52 at H.C. Wainwright
09/14/20 Jefferies
Inhibrx initiated with a Buy at Jefferies
AMGN Amgen
$234.68 /

-2.06 (-0.87%)

04/28/21 Atlantic Equities
Amgen downgraded to Underweight from Neutral at Atlantic Equities
04/28/21 Credit Suisse
Amgen price target lowered to $259 from $265 at Credit Suisse
04/28/21 BMO Capital
Amgen price target lowered to $296 from $301 at BMO Capital
04/28/21 Piper Sandler
Piper Sandler cuts Amgen target to $255 after 'ugly' quarter

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$154.20 /

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Syndicate
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ABML

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Recommendations
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Hot Stocks
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R.R. Donnelley

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Chatham Asset Management,…

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Hot Stocks
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Recommendations
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JinkoSolar

$42.35 /

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GLJ Research analyst…

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$42.35 /

-1.48 (-3.38%)

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$42.35 /

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Downgrade
American Water downgraded to Underperform from Neutral at BofA » 07:04
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07:04
AWK

American Water

$176.78 /

-1.085 (-0.61%)

BofA downgraded American…

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AWK American Water
$176.78 /

-1.085 (-0.61%)

AWK American Water
$176.78 /

-1.085 (-0.61%)

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American Water upgraded to Buy from Hold at Argus
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$176.78 /

-1.085 (-0.61%)

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