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LXRX

Lexicon

$16.30

-0.08 (-0.49%)

, SNY

Sanofi

$47.36

-0.2 (-0.42%)

18:04
07/31/17
07/31
18:04
07/31/17
18:04

Lexicon exercises option under pact with Sanofi to co-promote sotagliflozin

Lexicon Pharmaceuticals (LXRX) announced that it has exercised its option under its collaboration and license agreement with Sanofi (SNY) to co-promote sotagliflozin, an investigational oral dual inhibitor of sodium-glucose cotransporters 1 and 2, for the treatment of type 1 diabetes in the U.S. The opt-in decision was based on positive data from three Phase 3 studies, inTandem1, inTandem2, and inTandem3 and is aligned to a planned regulatory filing in the U.S. Sanofi intends to file applications in the first half of 2018 for the EU and U.S. regulatory reviews of sotagliflozin for the treatment of type 1 diabetes, pending the full read out of Phase 3 data.

LXRX

Lexicon

$16.30

-0.08 (-0.49%)

SNY

Sanofi

$47.36

-0.2 (-0.42%)

  • 31

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LXRX Lexicon
$16.30

-0.08 (-0.49%)

03/07/17
SBSH
03/07/17
NO CHANGE
Target $28
SBSH
Buy
Lexicon price target raised to $28 from $24 at Citi
Citi analyst Yigal Nochomovitz raised his price target for Lexicon Pharmaceuticals to $28 saying the company's potential in diabetes remains underappreciated. Management's commentary on sotagliflozin should re-assure investors who remain unconvinced about the T1D thesis, Nochomovitz tells investors in a post-earnings research note. He keeps a Buy rating on Lexicon.
03/01/17
WEDB
03/01/17
NO CHANGE
WEDB
Lexicon price target raised to $38 from $33 at Wedbush
Wedbush analyst Liana Moussatos increased her price target on Lexicon after the FDA approved Lexicon's lead drug, Zermelo, for carcinoid syndrome. The analyst thinks that the company has several additional upcoming positive potential catalysts. She keeps an Outperform rating on the stock.
12/22/16
SBSH
12/22/16
NO CHANGE
Target $24
SBSH
Buy
Citi disagrees with market view on Lexicon Pharmaceuticals
After shares of Lexicon Pharmaceuticals fell 7% yesterday following data from the second Phase 3 testing sotagliflozin in Type 1 diabetes, Citi analyst Yigal Nochomovitz says he disagrees with the market view. Investors are "getting too bogged" down on the safety question, the analyst tells investors in a research note. The data "unambiguously solve a major clinical challenge" in Type 1, which is getting A1c lower without the expense of glycemic excursions and thus more hypos, Nochomovitz writes. He keeps a Buy rating on Lexicon with a $24 price target.
12/21/16
12/21/16
NO CHANGE

Lexicon's sotagliflozin meets primary endpoint in Phase 3 trial for diabetes
Lexicon Pharmaceuticals' pivotal inTandem2 Phase 3 clinical trial of sotagliflozin met its primary endpoint, showing a statistically significant reduction in A1C at 24 weeks in patients with type 1 diabetes on optimized insulin therapy. Top-line results from the Phase 3 study showed that patients treated with sotagliflozin had mean A1C reductions from baseline of 0.39% on 200mg once daily sotagliflozin dose and 0.37% on 400mg once daily sotagliflozin dose as compared to a reduction of 0.03% on placebo after 24 weeks of treatment, meeting the study's primary endpoint. This statistically significant and clinically meaningful improvement in A1C for both doses of sotagliflozin was achieved with a favorable overall safety profile in the study, including rates of severe hypoglycemia similar to placebo and low overall rates of diabetic ketoacidosis.
SNY Sanofi
$47.36

-0.2 (-0.42%)

07/31/17
ADAM
07/31/17
NO CHANGE
Target $522
ADAM
Buy
Dupixent authorization approval rate outweighs Q2 miss, says Canaccord
Regeneron (REGN) partner Sanofi (SNY) reported a "very high" 73%-83% prior authorization approval rate for Dupixent in Q2, which Canaccord analyst John Newman said outweighs the fact that sales for the drug at $30.6M were slightly below the $33M consensus forecast. The analyst, who sees rapid payor acceptance of Dupixent as "much more crucial" than the initial quarterly revenue, keeps a Buy rating and $522 price target on Regeneron shares.
07/31/17
PIPR
07/31/17
NO CHANGE
Target $557
PIPR
Overweight
Regeneron indicated lower after Sanofi earnings report, says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff says shares of Regeneron (REGN) are indicated lower after partner Sanofi (SNY) reported Q2 U.S. Dupixent sales of $30M in adults with atopic dermatitis. This was essentially in line with the consensus estimate of $33M, Tenthoff tells investors in a research note. He adds that over 5,100 physicians have prescribed and over 13,000 atopic dermatitis patients have been prescribed Dupixent as of July 26. The analyst views the launch stats as impressive and reiterates an Overweight rating on Regeneron with a $557 price target.
07/14/17
WELS
07/14/17
NO CHANGE
Target $41
WELS
Outperform
Wells says smallpox vaccine deal an 'excellent fit' for Emergent BioSolutions
Wells Fargo analyst David Maris said Emergent BioSolutions' (EBS) deal to acquire the ACAM2000 smallpox vaccine business of Sanofi (SNY) is "an excellent fit" and he is "encouraged" by its ability to identify and make a deal for such a "solid target." Maris keeps an Outperform rating and $41 price target on Emergent BioSolutions.
07/10/17
PIPR
07/10/17
NO CHANGE
Target $126
PIPR
Overweight
Alnylam shares overreacting to ALT elevations in OLE data, says Piper Jaffray
Alnylam (ALNY) and partner Sanofi (SNY) presented new Phase II open-label extension study data on 33 hemophilia patients being treated with fitusiran and reported that eleven patients reported asymptomatic ALT increases, up from three observed in its ASH meeting update, noted Piper Jaffray analyst Edward Tenthoff. However, he thinks the stock is overreacting, as the liver enzyme elevations were asymptomatic and largely reversed within one month, he tells investors. Tenthoff, who also sees the efficacy data as encouraging, reiterates his Overweight rating and $126 price target on Alnylam shares.

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SPN

Superior Energy

$8.81

-0.14 (-1.56%)

21:18
11/20/17
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21:18
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21:18
Upgrade
Superior Energy rating change at SunTrust »

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MDT

Medtronic

$78.90

-0.59 (-0.74%)

, LOW

Lowe's

$81.46

1.24 (1.55%)

20:25
11/20/17
11/20
20:25
11/20/17
20:25
Earnings
Notable companies reporting before tomorrow's open »

Notable companies…

MDT

Medtronic

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-0.59 (-0.74%)

LOW

Lowe's

$81.46

1.24 (1.55%)

ADI

Analog Devices

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2.65 (2.93%)

DLTR

Dollar Tree

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2.5 (2.64%)

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Hormel Foods

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0.28 (0.85%)

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Campbell Soup

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Burlington Stores

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SIG

Signet Jewelers

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DSW

DSW

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CCLP

CSI Compressco

$5.28

-0.16 (-2.94%)

19:32
11/20/17
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19:32
Hot Stocks
CSI Compressco names Owen Serjeant president »

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AMAT

Applied Materials

$57.62

1.13 (2.00%)

, AAPL

Apple

$169.98

-0.17 (-0.10%)

19:04
11/20/17
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19:04
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19:04
Periodicals
Applied Materials expected to purchase former Apple complex, Mercury News says »

An office complex that…

AMAT

Applied Materials

$57.62

1.13 (2.00%)

AAPL

Apple

$169.98

-0.17 (-0.10%)

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FOX

21st Century Fox

$29.90

-0.58 (-1.90%)

, FOXA

21st Century Fox

$30.66

-0.49 (-1.57%)

18:21
11/20/17
11/20
18:21
11/20/17
18:21
Periodicals
Fox reaches $90M settlement over sexual harassment scandal, Reuters says »

21st Century Fox reached…

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21st Century Fox

$29.90

-0.58 (-1.90%)

FOXA

21st Century Fox

$30.66

-0.49 (-1.57%)

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BABA

Alibaba

$188.00

2.87 (1.55%)

18:19
11/20/17
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18:19
Hot Stocks
Muddy Waters says Alibaba numbers 'obviously fake' »

Short seller Muddy Waters…

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PANW

Palo Alto Networks

$142.53

-0.19 (-0.13%)

, CHKP

Check Point

$102.98

0.83 (0.81%)

18:15
11/20/17
11/20
18:15
11/20/17
18:15
Recommendations
Palo Alto Networks, Check Point, Fortinet analyst commentary at JPMorgan »

Palo Alto quarter…

PANW

Palo Alto Networks

$142.53

-0.19 (-0.13%)

CHKP

Check Point

$102.98

0.83 (0.81%)

FTNT

Fortinet

$40.77

0.46 (1.14%)

03/08/13
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AMZN

Amazon.com

$1,126.31

-3.57 (-0.32%)

18:14
11/20/17
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18:14
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18:14
Hot Stocks
Amazon announces cloud software for U.S spy agencies AWS Secret Region »

Amazon announced the new…

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BIVV

Bioverativ

$50.76

-5.35 (-9.53%)

, RHHBY

Roche

$30.82

1.72 (5.91%)

18:08
11/20/17
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18:08
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18:08
Recommendations
Deutsche cuts Bioverativ target to $53 after positive Roche data »

Deutsche Bank analyst…

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Bioverativ

$50.76

-5.35 (-9.53%)

RHHBY

Roche

$30.82

1.72 (5.91%)

SHPG

Shire

$141.37

-6 (-4.07%)

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CUBI

Customers Bancorp

$27.04

0.28 (1.05%)

18:04
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Hot Stocks
Customers Bancorp: Flagship could raise capital in IPO transaction in 1H18 »

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T

AT&T

$34.64

0.13 (0.38%)

, TWX

Time Warner

$87.71

-1.01 (-1.14%)

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Hot Stocks
AT&T CEO says has offered DOJ solutions that were not accepted »

Says DOJ suit throws lots…

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AT&T

$34.64

0.13 (0.38%)

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Time Warner

$87.71

-1.01 (-1.14%)

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NGD

New Gold

$3.21

-0.02 (-0.62%)

18:02
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Hot Stocks
New Gold announces sale of Peak Mines for $58M »

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IMI

Intermolecular

$1.31

0.1 (8.26%)

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Intermolecular partners with SITRI to develop MtM technologies »

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CMCSA

Comcast

$35.83

-0.33 (-0.91%)

18:00
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18:00
Initiation
Comcast initiated at Buckingham »

Comcast initiated with an…

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MLNX

Mellanox

$51.05

1 (2.00%)

17:59
11/20/17
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Hot Stocks
Mellanox up nearly 6% after Starboard discloses a 9.8% stake in the company »

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PLNT

Planet Fitness

$30.15

0.07 (0.23%)

17:58
11/20/17
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17:58
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17:58
Initiation
Planet Fitness initiated at DA Davidson »

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TER

Teradyne

$44.43

0.86 (1.97%)

17:57
11/20/17
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17:57
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17:57
Downgrade
Teradyne rating change at Deutsche Bank »

Teradyne downgraded to…

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CBS

CBS

$55.93

-0.81 (-1.43%)

17:56
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Periodicals
CBS News suspends Charlie Rose following sexual harassment claims, AP says 

Reference Link

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CBS

CBS

$55.93

-0.81 (-1.43%)

17:55
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Periodicals
Eight women accuse Charlie Rose of sexual harassment, Washington Post says »

Eight women have said…

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MLNX

Mellanox

$51.05

1 (2.00%)

, MRVL

Marvell

$21.59

1.3 (6.41%)

17:53
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Hot Stocks
Starboard Value reports 9.8% stake in Mellanox, may seek talks »

Peter A. Feld, a…

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Mellanox

$51.05

1 (2.00%)

MRVL

Marvell

$21.59

1.3 (6.41%)

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CDXS

Codexis

17:46
11/20/17
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17:46
Hot Stocks
Breaking Hot Stocks news story on Codexis »

Telemark Asset Management…

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T

AT&T

$34.64

0.13 (0.38%)

, TWX

Time Warner

$87.71

-1.01 (-1.14%)

17:45
11/20/17
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17:45
Hot Stocks
AT&T CEO says giving up control of CNN is a 'non-starter' »

Says plenty of solutions…

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AT&T

$34.64

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Time Warner

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-1.01 (-1.14%)

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  • 29

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BBY

Best Buy

$56.35

0.52 (0.93%)

17:45
11/20/17
11/20
17:45
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17:45
Conference/Events
Best Buy management to meet with SunTrust »

Group dinner to be held…

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T

AT&T

$34.64

0.13 (0.38%)

, TWX

Time Warner

$87.71

-1.01 (-1.14%)

17:43
11/20/17
11/20
17:43
11/20/17
17:43
Hot Stocks
AT&T CEO says DOJ suit 'defies logic' »

Says has offered…

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AT&T

$34.64

0.13 (0.38%)

TWX

Time Warner

$87.71

-1.01 (-1.14%)

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